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Cefdinir
go.drugbank.com/drugs/DB00535ApprovedInvestigationalCefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially marketed by Abbvie.
Polymyxin B
go.drugbank.com/drugs/DB00781ApprovedInvestigationalVet approvedPolymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label]. … It is appropriate for treatment of infections of the urinary tract, meninges, and blood stream, caused by susceptible strains of _Pseudomonas aeruginosa_[FDA Label].
Mixtures: Bus and Classroom Yellow, Care Bus and Classroom YellowChikungunya virus Senegal strain 37997 capsid protein
go.drugbank.com/drugs/DB21766ApprovedInvestigationalOne of three components of a recombinant Chikungunya virus vaccine called Vimkunya.
Chikungunya virus Senegal strain 37997 envelope protein E2
go.drugbank.com/drugs/DB21768ApprovedInvestigationalOne of three components of a recombinant Chikungunya virus vaccine called Vimkunya.
Rivaroxaban
go.drugbank.com/drugs/DB06228ApprovedInvestigationalOnly the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. FDA approved on July 1, 2011.
Brimonidine
go.drugbank.com/drugs/DB00484ApprovedInvestigational[A178948,A178969] Ophthalmically, brimonidine is used to lower intraocular pressure by reducing aqueous humor production and increasing uveoscleral outflow. … [A178948] The topical form of brimonidine was approved by the FDA in August 2013 for the symptomatic treatment of persistent facial erythema of rosacea in adults.
Telithromycin
go.drugbank.com/drugs/DB00976ApprovedSimilar to the macrolide antibiotics, telithromycin prevents bacterial growth by interfering with bacterial protein synthesis. … Binding occurs simultaneously at to two domains of 23S RNA of the 50S ribosomal subunit, domain II and V, where older macrolides bind only to one.
Sulbactam
go.drugbank.com/drugs/DB09324ApprovedInvestigational[L50131] When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.[A263296]
Mixtures: Ampicillin/Sulbactam Astro 3 g Pulver zur Herstellung einer Injektions- oder Infusionslösung, Ampicillin/Sulbactam Astro 1,5 g Pulver zur Herstellung einer Injektions- oder InfusionslösungZinc chloride
go.drugbank.com/drugs/DB14533ApprovedZinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc levels and prevent deficiency syndromes. Zinc chloride was granted FDA approval before 26 June 1986.
Sugemalimab
go.drugbank.com/drugs/DB16641ApprovedInvestigational[L32868, L32873, L53333] The antibody is produced in Chinese hamster ovary cells by recombinant DNA technology. … Sugemalimab is a fully human, full-length anti-programmed death-ligand 1 (PD-L1) monoclonal antibody (of the IgG4 isotype) discovered by CStone Pharmaceuticals.