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Canakinumab
go.drugbank.com/drugs/DB06168ApprovedInvestigationalwell as for patients 2 years of age and older to treat systemic juvenile idiopathic arthritis (SJIA). … It is expressed in a murine Sp2/0-Ag14 cell line and comprised of two 447- (or 448-) residue heavy chains and two 214-residue light chains, with a molecular mass of 145157 Daltons when deglycosylated.
Products: ILARIS® SOLUCIÓN INYECTABLE 150 MG/ ML, İLARİS 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADETMometasone
go.drugbank.com/drugs/DB00764ApprovedInvestigationalMometasone is a corticosteroid not currently used in medical products. Mometasone furoate however, is still in use.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: MOMENSA (50 ตg/ACTUATION NASAL SPRAY , SUSPENSION), AIRMETA 200 MCG INHALASYON ICIN TOZ ICEREN BLISTER, 60 DOZSelenious acid
go.drugbank.com/drugs/DB11127ApprovedIt also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. … Interestingly, selenium is being studied as a potential therapy in the prevention or management of atherosclerosis [L1921].
Mixtures: TRACUTIL® 10 ML AMPOLLAS, Multitrace-5Products: Selenase 500 Mikrogramm/10 ml - Lösung zum Einnehmen, Selen Aguettant 10 Mikrogramm/ml Konzentrat zur Herstellung einer InfusionslösungNaloxone
go.drugbank.com/drugs/DB01183ApprovedInvestigationalVet approved[A234594] More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist, causing the rapid removal of any other drugs bound to these receptors. … [L33714,L33719] The primary purpose of including naloxone within Suboxone is to act as a deterrent to injection, as injected naloxone would rapidly reverse the effects of buprenorphine.
Mixtures: Targin 10 mg/5 mg Retardtabletten, Oxylanox 10 mg/5 mg-RetardtablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsSimvastatin
go.drugbank.com/drugs/DB00641ApprovedInvestigational[A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular … [A181397, A181403] While all statin medications are considered equally effective from a clinical standpoint, [rosuvastatin] is considered the most potent; doses of 10 to 40mg [rosuvastatin] per day
Mixtures: SimEz 10 mg/10 mg Tabletten, Ezesim 10 mg/10 mg-TablettenCategories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesRabeprazole
go.drugbank.com/drugs/DB01129ApprovedInvestigationalRabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric...
Mixtures: RABEDIC MR 20/100 MG KAPSÜL, 20 ADET, RABEDIC MR 20/100 MG KAPSÜL, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersSennosides
go.drugbank.com/drugs/DB11365ApprovedInvestigationalSennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label][L771] and empty the large intestine before surgery. … Sennoside A, one of the sennosides present in the laxative medication, has recently proven effective in inhibiting the ribonuclease H (RNase H) activity of human immunodeficiency virus (HIV) reverse transcriptase
Mixtures: Sennosides 8.6 Mg and Docusate Sodium 50 Mg Tablets, Senna Plus Standardized Senna Concentrate 8.6 mg and Docusate Sodium 50 mg EachProducts: ROHA LAX 20 MG/5 ML GRANÜL, 150 ML, SENOKOT 7.5 MG TABLET, 50 ADETPanitumumab
go.drugbank.com/drugs/DB01269ApprovedInvestigationalPanitumumab was granted FDA approval on 27 September 2006.[L17663]
Products: Vectibix Concentrate for Solution for Infusion 100 mg/vial, VECTIBIX 20 MG/ML 5 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADETAllantoin
go.drugbank.com/drugs/DB11100ApprovedInvestigationalIn healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. … The concentration of allantoin in muscles increases from a resting value of about 5000 ug/kg to about 16000 ug/kg immediately after short-term exhaustive cycling exercise [FDA Label].
Synonyms: SD-101, 5-UreidohydantoinMixtures: NOSKAR 100 MG/50 IU/10 MG / G, JEL 50 G, NOSKAR 100 MG/50 IU/10 MG / G, JEL 100 GNorepinephrine
go.drugbank.com/drugs/DB00368ApprovedInvestigationalIt is also found in plants and is used pharmacologically as a sympathomimetic.
Mixtures: XYLONOR %3 NORADRENALINE ENJEKSIYONLUK SOLUSYON ICEREN KULLANIMA HAZIR 50 KARTUSProducts: EPINOR 4 MG/4 ML IV INFÜZYONLUK KONSANTRE ÇÖZELTİ,10 AMPUL, FOREFRIN 4 MG/4 ML I.V. INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL, 10 AMPUL