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FG-2216
go.drugbank.com/drugs/DB08687InvestigationalA orally active prolyl-hydroxylase inhibitor which can stabilize hypoxia-inducible transcription factor independent of oxygen availability.
Synonyms: (((1-Chloro-4-hydroxyisoquinolin-3-yl)carbonyl)amino)acetic acidCapadenoson
go.drugbank.com/drugs/DB16118InvestigationalCapadenoson is under investigation in clinical trial NCT00518921 (Capadenoson in Angina Pectoris).
Enibarcimab
go.drugbank.com/drugs/DB16730InvestigationalEnibarcimab is under investigation in clinical trial NCT03989531 (Adrecizumab in Cardiogenic Shock).
MF-300
go.drugbank.com/drugs/DB32060InvestigationalMF-300 is an investigational, first-in-class, small molecule inhibitor of 15-hydroxyprostaglandin dehydrogenase. … As a potential candidate for the treatment of sarcopenia, it has undergone phase 1 studies to evaluate safety, tolerability, and PK/PD characteristics.[A275368,L54983]
MGC030
go.drugbank.com/drugs/DB33973ExperimentalMGC030 is a biologic drug. MGC030 is under investigation in clinical trial NCT07822399 (A Study of MGC030 in Participants With Advanced Solid Tumors).
CoronaVac
go.drugbank.com/drugs/DB15806InvestigationalIn preclinical trials, PiCoVacc induced SARS-CoV-2-specific neutralizing antibodies in rats, mice, and the rhesus macaque. … As of August 2020, the vaccine is being tested in numerous human clinical trials assessing its safety and immunogenicity.
TPMPA
go.drugbank.com/drugs/DB16754ExperimentalTPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABA<sub>C</sub> receptors (also known as GABA-ρ or GABA<sub>A-ρ</sub> receptors). … [A245303] GABA<sub>C</sub> receptors are found primarily in the retina, although they may be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and the gut
Synonyms: (1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acidQazCovid-in
go.drugbank.com/drugs/DB16441InvestigationalIt demonstrated high efficacy, safety, and immunogenicity at 96% in initial Phase I and II trials (NCT04530357), and will now be undergoing upcoming Phase III trials[L30633, L30638]. … The QazCovid-in vaccine, an inactivated vaccine, was developed and tested in the Kazakh Research Institute for Biological Safety Problems[L30628].