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Displaying results 7001 - 7010 of 10000 in total
  1. Drug

    MK-8189

    go.drugbank.com/drugs/DB19153
    Investigational

    MK-8189 is under investigation in clinical trial NCT04624243 (Efficacy and Safety of MK-8189 in Participants With an Acute Episode of Schizophrenia (MK-8189-008)).

    Synonyms: 4-PYRIMIDINAMINE, 2-METHYL-6-(((1S,2S)-2-(5-METHYL-2-PYRIDINYL)CYCLOPROPYL)METHOXY)-N-((5-METHYL-1,3,4-THIADIAZOL-2-YL)METHYL)-
  2. Drug

    Pamapimod

    go.drugbank.com/drugs/DB19169
    Investigational

    Pamapimod is under investigation in clinical trial NCT05659459 (The KIN-FAST Trial (KIN001 for Accelerated Symptoms Termination) in Non Hospitalized Patients Infected With Sars-cov-2).

  3. Drug

    Enarodustat

    go.drugbank.com/drugs/DB14985
    Investigational

    Enarodustat is under investigation in clinical trial NCT02581124 (Study to Evaluate Effect of Lapatinib on Pharmacokinetics of JTZ-951 in Subjects With End-stage Renal Disease).

  4. Drug

    Dubermatinib

    go.drugbank.com/drugs/DB15187
    Investigational

    Dubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL).

  5. Drug

    Gamcemetinib

    go.drugbank.com/drugs/DB21624
    Investigational

    Gamcemetinib is under investigation in clinical trial NCT04947579 (A Study of CC-99677 in Participants With Active Ankylosing Spondylitis). … Gamcemetinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Gamcemetinib is a tyrosine kinase inhibitor.

  6. Drug

    Magnesium orotate

    go.drugbank.com/drugs/DB13786
    Experimental

    Magnesium orotate is a magnesium salt of orotic acid and is poorly soluble in water. It is a source of magnesium and is used as a mineral supplement to treat Mg deficiency. … It also exhibits antioxidant properties, since it is a key intermediate in the biosynthetic pathway of pyrimidines that promotes the synthesis of enzymes which act as free radical scavengers.

  7. Drug

    Betulinic Acid

    go.drugbank.com/drugs/DB12480
    ApprovedWithdrawn

    Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.

  8. Drug

    5-O-phosphono-alpha-D-ribofuranosyl diphosphate

    go.drugbank.com/drugs/DB01632
    ApprovedWithdrawn

    The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.

  9. Drug

    Efavaleukin alfa

    go.drugbank.com/drugs/DB16149
    Investigational

    It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With Steroid Refractory Chronic Graft Versus Host Disease). … Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin G Fc domain by way of a G4S linker.

    Synonyms: Fc il-2 mutein fusion protein (amg-592)
  10. Drug

    Obicetrapib

    go.drugbank.com/drugs/DB14890
    Investigational

    Obicetrapib is under investigation in clinical trial NCT02241772 (A Study on the Effects of TA-8995 on Lp(a) in Subjects With Elevated Lp(a)).