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SCB-2019
go.drugbank.com/drugs/DB15805InvestigationalThis vaccine candidate resembles the native trimeric viral spike and is produced through mammalian cell-culture. The vaccine was developed and tested by Clover Biopharmaceuticals AUS Pty Ltd.. … As of June 2020, the company is pursuing a randomized, double blind, placebo controlled study (NCT04405908) to test the safety and immunogenicity of the vaccine.
Ramoplanin
go.drugbank.com/drugs/DB04952ExperimentalRamoplanin is a novel glycolipodepsipeptide antibiotic under development for the treatment of CDAD.
Categories: Amino Acids, Peptides, and ProteinsNorflurane
go.drugbank.com/drugs/DB13116ApprovedInvestigationalWithdrawnNorflurane is under investigation in clinical trial NCT01673061 (Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage).
B-cell receptor CD22
go.drugbank.com/bio_entities/BE0000183TargetHumansCan also bind to ligands on other cells as an adhesion molecule in a trans configuration (PubMed:20172905). … Binds to alpha 2,6-linked sialic acid residues of surface molecules such as CD22 itself, CD45 and IgM in a cis configuration.
Synonyms: BL-CAMKBP-COVID-19
go.drugbank.com/drugs/DB15858InvestigationalKBP cloned COVID-19’s genetic sequence, identified a potential antigen, and then inserted it into tobacco plants for reproduction. … Upon harvest, the antigens were purified, and these components underwent preclinical testing in animals.
Apazunersen
go.drugbank.com/drugs/DB16981InvestigationalApazunersen is an antisense oligonucleotide designed to target and inhibit the expression of UBE3A-AS. It is being investigated for the treatment of Angelman Syndrome.[L46772]
AVR-RD-02
go.drugbank.com/drugs/DB17650InvestigationalAVR-RD-02 is an investigational _ex vivo_ lentiviral gene therapy developed by AVROBIO Inc. … AVR-RD-02 is being investigated in Gaucher Disease.[L45958]
Indocyanine green
go.drugbank.com/drugs/DB16024ApprovedInvestigationalWithdrawnCategories: Compounds used in a research, industrial, or household settingPrinomastat
go.drugbank.com/drugs/DB05100InvestigationalPrinomastat inhibits matrix metalloproteinases (MMPs) (specifically, MMP-2, 9, 13, and 14), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and … Prinomastat is a synthetic hydroxamic acid derivative with potential antineoplastic activity.