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Zavacorilant
go.drugbank.com/drugs/DB21509InvestigationalZavacorilant is under investigation in clinical trial NCT04672512 (Single and Multiple Ascending Dose Study of CORT125329 in Healthy Participants). … Zavacorilant is a small molecule drug. The usage of the INN stem '-corilant' in the name indicates that Zavacorilant is a glucocorticoid receptor antagonist (non-steroidal).
Xiliertinib
go.drugbank.com/drugs/DB21453InvestigationalXiliertinib is a small molecule drug. The usage of the INN stem '-ertinib' in the name indicates that Xiliertinib is a epidermal growth factor receptor (EGFR) inhibitor. … Xiliertinib is under investigation in clinical trial NCT02601274 (Study of Theliatinib (HMPL-309) in Patients With Advanced Solid Tumor). Xiliertinib has a monoisotopic molecular weight of 442.21 Da.
Paltimatrectinib
go.drugbank.com/drugs/DB21588InvestigationalPaltimatrectinib is under investigation in clinical trial NCT04901806 (Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors). … Paltimatrectinib is a small molecule drug. The usage of the INN stem '-trectinib' in the name indicates that Paltimatrectinib is a tropomyosin receptor kinase (TRK) inhibitor.
Mitazalimab
go.drugbank.com/drugs/DB15225InvestigationalMitazalimab is under investigation in clinical trial NCT02379741 (ADC-1013 First-in-Human Study).
Methcathinone
go.drugbank.com/drugs/DB15339ExperimentalMethcathinone is under investigation in clinical trial NCT02617862 (PCI Imaging System in Pediatric Ophthalmology).
SER-100
go.drugbank.com/drugs/DB16013InvestigationalSER-100 is under investigation in clinical trial NCT01987284 (SER100 in Isolated Systolic Hypertension).
Opnurasib
go.drugbank.com/drugs/DB21583InvestigationalOpnurasib is a small molecule drug. The usage of the INN stem '-rasib' in the name indicates that Opnurasib is a Ras protein inhibitor. … Opnurasib is under investigation in clinical trial NCT05132075 (Study of JDQ443 in Comparison With Docetaxel in Participants With Locally Advanced or Metastatic KRAS G12C Mutant Non-small Cell Lung Cancer
Reloxaliase
go.drugbank.com/drugs/DB15560InvestigationalReloxaliase is under investigation in clinical trial NCT03456830 (Evaluate ALLN-177 in Patients With Enteric Hyperoxaluria). … Reloxaliase is a crystalline formulation of oxalate decarboxylase derived from _Bacillus Subtilis_.
AEF0117
go.drugbank.com/drugs/DB27675InvestigationalAEF0117 is a small molecule drug. AEF0117 is under investigation in clinical trial NCT05554926 (Study of [4-14C] AEF0117 Following a Single Oral Dose in Healthy Male Subjects).