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mRNA-1345
go.drugbank.com/drugs/DB18739ApprovedInvestigationalmRNA-1345 is a nucleoside modified mRNA encoding the F-glycoprotein from RSV subtype A stabilized in its prefusion conformation.[L53393] It is the primary ingredient of the RSV vaccine mRESVIA.
Categories: Complex MixturesAdrenomedullin
go.drugbank.com/drugs/DB19102InvestigationalAdrenomedullin is under investigation in clinical trial NCT06072118 (Adrenomedullin for CADASIL).
Categories: Compounds used in a research, industrial, or household settingDeuterium oxide
go.drugbank.com/drugs/DB19251InvestigationalSynonyms: Water-D sub(2)Categories: Compounds used in a research, industrial, or household settingLepirudin
go.drugbank.com/drugs/DB00001ApprovedWithdrawnLepirudin is a recombinant hirudin formed by 65 amino acids that acts as a highly specific and direct thrombin inhibitor. … [A3, L41539] HIT is caused by the expression of immunoglobulin G (IgG) antibodies that bind to the complex formed by heparin and platelet factor 4.
Salmon calcitonin
go.drugbank.com/drugs/DB00017ApprovedInvestigationalSynthetic peptide, 32 residues long formulated as a nasal spray.
Antihemophilic factor, human recombinant
go.drugbank.com/drugs/DB00025ApprovedInvestigationalHuman recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Categories: Hemophilia ACoagulation factor VIIa Recombinant Human
go.drugbank.com/drugs/DB00036ApprovedInvestigationalNovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Lyme disease vaccine (recombinant OspA)
go.drugbank.com/drugs/DB00045ApprovedWithdrawnLipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as an adjuvant.
Synonyms: Lipoprotein outer surface a borrelia burgdorferi antigenEptifibatide
go.drugbank.com/drugs/DB00063ApprovedInvestigationalDerived from venom of the Southeastern pygmy rattlesnake (Sistrurus miliarus barbouri), eptifibatide is a cyclic heptapeptide that belongs to the class of arginin-glycin-aspartat-mimetics.
Hyaluronidase (ovine)
go.drugbank.com/drugs/DB00070ApprovedHighly purified sheep hyaluronidase for administration by injection into the vitreous of the eye.