Search
Teriflunomide
go.drugbank.com/drugs/DB08880ApprovedInvestigationalThe FDA label states an important warning about the risk of hepatoxicity and teratogenicity for patients using teriflunomide. … Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis.
Products: TERIFLUNOMIDE EGEzetimibe
go.drugbank.com/drugs/DB00973ApprovedInvestigationalC1-Like 1 (NPC1L1), and is unique in that it does not affect the absorption of fat-soluble nutrients such as fat-soluble vitamins, triglycerides, or bile acids. … [A33313] In genetically NPC1L1-deficient mice, a 70% reduction in intestinal cholesterol absorption was seen, and these mice were insensitive to ezetimibe treatment - it was determined based on these findings
Mixtures: TIAZOMET ® A 40/10 TABLETAS, EZETIMIBE E SIMVASTATINA EGCategories: Hypolipidemic Agents Indicated for Hyperlipidemia, Non-statin Hypolipidemic Agents Indicated for HyperlipidemiaAluminum chlorohydrate
go.drugbank.com/drugs/DB11573ApprovedIt is also used as a coagulant in the water purification process. … Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m.
Mixtures: Watkins Roll On Deodorant, Anti-perspirant Roll-ON DeodCategories: Drugs for Treatment of Bone DiseasesCilostazol
go.drugbank.com/drugs/DB01166ApprovedInvestigationalCilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia
Categories: Compounds used in a research, industrial, or household settingProducts: CILOSTAZOLO EG, CILOSTAZOL AL 50MG TABCabazitaxel
go.drugbank.com/drugs/DB06772ApprovedInvestigationalCabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. … It was first approved by the FDA on June 17, 2010.[A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17, 2019.[L47376]
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexSynonyms: -DIMETHOXY-9-OXO-5.BETA.,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA.-TRIYL 4-ACETATE 2-BENZOATE 13-((2R,3S)-3-(((TERT-BUTOXY)CARBONYL)AMINO)-2-HYDROXY-3-PHENYLPROPANOATE)Cinacalcet
go.drugbank.com/drugs/DB01012ApprovedInvestigationalCinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe. … It is used to treat hyperparathyroidism due to parathyroid tumours or renal failure.
Synonyms: (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine, N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amineProducts: CINACALCET EG, TICAGRELOR EGRifaximin
go.drugbank.com/drugs/DB01220ApprovedInvestigationalRifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic, meaning that the drug will not pass the gastrointestinal wall into the circulation as is common for other types of orally administered … syndrome (IBS-D) in adult women and men.
Categories: Antibiotics for Topical Use, Heterocyclic Compounds with 4 or More RingsSynonyms: Rifamycin L 105, Rifamycin L 105SVDexibuprofen
go.drugbank.com/drugs/DB09213ApprovedWithdrawnDexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. … For Metabolism, Enzymes, Carriers, Transporters Sections, refer to [Ibuprofen].
Products: Eu-Med 200 mg SchmerztablettenAtorvastatin
go.drugbank.com/drugs/DB01076ApprovedInvestigationalor angioplasty following a heart attack. … the number of major cardiovascular events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks.
Mixtures: BLODIVIT-EZ, TIAZOMET ® A 40/10 TABLETASCategories: Hypolipidemic Agents Indicated for HyperlipidemiaTrimebutine
go.drugbank.com/drugs/DB09089ApprovedInvestigationalTrimebutine is not a FDA-approved drug, but it is available in Canada and several other international countries. … It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI disorders [A19691].
Categories: Drugs for Functional Gastrointestinal DisordersInternational brands: Yuan Sheng Li Wei