Search

Displaying results 701 - 710 of 10000 in total
  1. Drug

    Secnidazole

    go.drugbank.com/drugs/DB12834
    ApprovedInvestigational

    [A27210] Once it enters bacteria and parasites, secnidazole is activated by bacterial or parasitic enzymes to form a radical anion, thereby damaging and killing the target pathogen. … Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: SECNICHEN POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL, SECNIDAZOL PPS (POLVO PARA RECONSTITUIR A SUSPENSIÓN)
  2. Drug

    Ibrexafungerp

    go.drugbank.com/drugs/DB12471
    Approved

    Ibrexafungerp, also known as SCY-078 or MK-3118, is a novel enfumafungin derivative oral triterpene antifungal approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast … [A235384,L34349] It was developed out of a need to treat fungal infections that may have become resistant to echinocandins or azole antifungals.

    Categories: Antimycotics for Systemic Use, Antiinfectives for Systemic Use
  3. Drug

    Tavaborole

    go.drugbank.com/drugs/DB09041
    Approved

    Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to *Trichophyton rubrum* or *Trichophyton mentagrophytes … Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis of ATP-dependent ligation of L-leucine to tRNA(Leu).

    Categories: Antifungals for Topical Use, Antifungals for Dermatological Use
  4. Drug

    Riociguat

    go.drugbank.com/drugs/DB08931
    ApprovedInvestigational

    Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for … Treatment with riociguat costs USD $7,500 for 30 days of treatment.

    Categories: Antihypertensives for Pulmonary Arterial Hypertension
  5. Drug

    Narsoplimab

    go.drugbank.com/drugs/DB16418
    ApprovedInvestigational

    [A241030] Evidence increasingly points to a role for the complement system in TMA. … [A241030, A241040] Narsoplimab (OMS721), a human IgG4λ anti-MASP-2 antibody, is under consideration as a treatment for hematopoietic stem cell transplant-associated TMA (HSCT-TMA/TA-TMA) and IgA nephropathy

  6. Drug

    Sodium tetradecyl sulfate

    go.drugbank.com/drugs/DB00464
    Approved

    An anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins.

    Categories: Compounds used in a research, industrial, or household setting, Sclerosing Agents for Local Injection
  7. Drug

    Isometheptene

    go.drugbank.com/drugs/DB06706
    Approved

    Isometheptene is a sympathomimetic drug that causes vasoconstriction. It is used for treating migraines and tension headaches.

    Categories: Drugs for Functional Gastrointestinal Disorders
  8. Drug

    Potassium hydroxide

    go.drugbank.com/drugs/DB11153
    Approved

    Recently, it has been studied for efficacy and tolerability in the treatment of warts. … Potassium hydroxide is also a precursor to other potassium compounds. Potassium hydroxide is used in food to adjust pH, as a stabilizer, and as a thickening agent.

    Mixtures: Kalium-L-malat "Fresenius" 1 molar - Infusionszusatz - Ampullen, Nutriflex Peri Solution for InfusionCategories: Compounds used in a research, industrial, or household setting
  9. Drug

    Telaprevir

    go.drugbank.com/drugs/DB05521
    ApprovedWithdrawn

    Telaprevir was available as a fixed dose product (tradename Incivek) used for the treatment of chronic Hepatitis C. … The substitutions of the enzyme's catalytic triad consisting of H58, D82, and S139 are also likely to alter the affinity of the drug for NS3/4A or the activity of the enzyme itself.

    Categories: NS3/4A Protease Inhibitors, HCV NS3/4A Protease InhibitorsSynonyms: (1S,3aR,6aS)-(2S)-2-cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-((1S)-1-((cyclopropylamino)oxoacetyl)butyl)octahydrocyclopenta(c)pyrrole-1-carboxamide
  10. Drug

    Bacitracin

    go.drugbank.com/drugs/DB00626
    ApprovedInvestigationalVet approved

    Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. … [A181952] The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy.

    Mixtures: Pomada De La Campana Triple Antibiotic Pain Relief, Tribioticlc Lc LcCategories: Antibiotics for Topical Use, Antibacterials for Systemic Use