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Trimethoprim
go.drugbank.com/drugs/DB00440ApprovedInvestigationalVet approved[L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of … [L11893,L11830] It is structurally and chemically related to [pyrimethamine], another antifolate antimicrobial used in the treatment of plasmodial infections.[T707]
Mixtures: Riva-sep DS, Sulfamethoxazole and Trimethoprim for Injection, USPCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseVismodegib
go.drugbank.com/drugs/DB08828ApprovedInvestigationalAfterwards, it is silenced in all cells and tissues, except for hair, skin and stem cells. … Vismodegib is an orally active small molecule that inhibits the hedgehog signaling pathway by binding to and inhibiting the transmembrane protein smoothened homologue (SMO).
Secnidazole
go.drugbank.com/drugs/DB12834ApprovedInvestigationalSecnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. … Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent.
Mixtures: FUNEX® - S TABLETA, BATEN ® S TABLETAS RECUBIERTASCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseMestranol
go.drugbank.com/drugs/DB01357ApprovedWithdrawnIt is used as the estrogen component of many combination ORAL contraceptives.
Categories: Hormonal Contraceptives for Systemic UseAdipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic Origins
go.drugbank.com/drugs/DB15729InvestigationalAdipose mesenchymal stem cells (AMSCs) are MSCs derived from adipose tissue, which is more accessible and less painful than stem cells extracted from most other sources. … Autologous stem cells are those derived from a patient’s own cells while allogeneic stem cells are derived from that of a donor.
Synonyms: Adipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic OriginsDornase alfa
go.drugbank.com/drugs/DB00003ApprovedInvestigationalDornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. … In individuals with cystic fibrosis, extracellular DNA, which is an extremely viscous anion, is released by degenerating leukocytes that accumulate during inflammatory responses to infections.
Amivantamab
go.drugbank.com/drugs/DB16695ApprovedInvestigational[L41469] On December 17, 2025, the U.S. … FDA approved the subcutaneous formulation, RYBREVANT FASPRO™, across all existing and expanded indications of amivantamab, including its use as a first-line, chemotherapy-free combination regimen with
Levonorgestrel
go.drugbank.com/drugs/DB00367ApprovedInvestigational[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. … [L7823] In addition to the above uses, levonorgestrel is used as a component of long-term combination contraceptives.
Mixtures: FEM 7 COMBI 50MCGCategories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemDiethylamino hydroxybenzoyl hexyl benzoate
go.drugbank.com/drugs/DB11269ApprovedDiethylamino hydroxybenzoyl hexyl benzoate is a UV filter with high absorption in the UV-A range. … It is used in concentrations up to 10% in sunscreen products, either alone or in combination with other UV absorbers [F107].
Mixtures: Premium Ultra Uv Pure Sun, MEDIKOii Bio-UV Protect Laser MasterCloxacillin
go.drugbank.com/drugs/DB01147ApprovedInvestigationalVet approvedA semi-synthetic penicillin antibiotic which is a chlorinated derivative of [oxacillin].
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseSynonyms: (2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid