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Clobetasol propionate
go.drugbank.com/drugs/DB01013ApprovedInvestigational[A190936] Clobetasol Propionate was granted FDA approval on 27 December 1985.[L11809]
Brivaracetam
go.drugbank.com/drugs/DB05541ApprovedInvestigationalBriviact received FDA approval on February 19, 2016 [L760].
Edetate calcium disodium anhydrous
go.drugbank.com/drugs/DB14598ApprovedInvestigational[A204173] Edetate calcium disodium was granted FDA approval on 16 July 1953.[L12774]
Terbutaline
go.drugbank.com/drugs/DB00871ApprovedInvestigational[A230333,L32093,L32098] Terbutaline was granted FDA approval on 25 March 1974.[L32088]
Atrasentan
go.drugbank.com/drugs/DB06199ApprovedInvestigational[L52855] In April 2025, atrasentan was granted accelerated approval by the FDA for the reduction of proteinuria in patients with primary IgA nephropathy, becoming the first endothelin A receptor antagonist
Trametinib
go.drugbank.com/drugs/DB08911ApprovedInvestigational[A258298,A258293] It was first approved by the FDA in May 2013 for the treatment of melanoma.
Ferrous fumarate
go.drugbank.com/drugs/DB14491ApprovedInvestigationalUsed in treatment of iron deficiency anemia.
Mixtures: FeRiva FA, Hematogen FAViper antivenom
go.drugbank.com/drugs/DB14114ApprovedInvestigationalANAVIP, an equine-derived antivenom made with venom from _Bothrops asper_ and _Crotalus durissus_, was first approved by the FDA on October 1, 2015, for the management of North American rattlesnake envenomation
Artesunate
go.drugbank.com/drugs/DB09274ApprovedInvestigational[A203948] Artesunate was granted FDA approval on 26 May 2020.[L14099]