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Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
go.drugbank.com/conditions/DBCOND0080506Drugs: Polatuzumab vedotinSynonyms: Malignant lymphoma, large B-cell, diffuse, no ICD-O subtype, Malignant lymphoma, large B-cell, diffuse, no International Classification of Diseases for Oncology subtypeLumefantrine
go.drugbank.com/drugs/DB06708ApprovedInvestigational</i> and may be used to treat infections caused by <i>P. falciparum</i> and unidentified <i>Plasmodium</i> species, including infections acquired in chloroquine-resistant areas. … Lumefantrine is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy.
Potassium citrate
go.drugbank.com/drugs/DB09125ApprovedInvestigationalVet approvedIt contains 38.3% potassium by mass. In the monohydrate form it is highly hygroscopic and deliquescent. Potassium citrate is used to treat a kidney stone condition called renal tubular acidosis.
Mixtures: Formula No. 2 Plus K Liq, UROCLASIO NFMoxisylyte
go.drugbank.com/drugs/DB09205Approved[T45] According to the WHO, moxisylyte is approved since 1987[T91] and in the same year, it acquired the denomination of orphan product by the FDA. … [L1172] This drug was developed by the Japanese company Fujirebio and also by the American company Iolab in the late 80s.
Doripenem
go.drugbank.com/drugs/DB06211ApprovedWithdrawnDoripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. … Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen.
Hetacillin
go.drugbank.com/drugs/DB00739ApprovedVet approvedWithdrawnHetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. … Hetacillin has been withdrawn from the market since it has been discovered that it has no therapeutic advantage compared to non-ester derivatives like ampicillin.
Ethinylestradiol
go.drugbank.com/drugs/DB00977ApprovedInvestigationalEthinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering.[A191107] It was developed in an effort to create an estrogen with greater oral bioavailability. … [A191107] These properties were achieved by the substitution of an ethinyl group at carbon 17 of [estradiol].[A191107] Ethinylestradiol soon replaced [mestranol] in contraceptive pills.
Mixtures: Lo/Ovral, Lo-ovral-28Chlorobutanol
go.drugbank.com/drugs/DB11386ApprovedVet approvedWithdrawnSimilar in nature to chloral hydrate, it is formed by the simple nucleophilic addition of chloroform and acetone. … Chlorobutanol, or chlorbutol, is an alcohol-based preservative with no surfactant activity [A32746].
Tozinameran
go.drugbank.com/drugs/DB15696ApprovedInvestigational[L15017, L15022] Comirnaty received fast track designation by the U.S. FDA on July 13, 2020. … [L36025] Currently, sufficient data are not available to determine the longevity of protection against COVID-19, nor direct evidence that the vaccine prevents the transmission of the SARS-CoV-2 virus
Pepsin
go.drugbank.com/drugs/DB13198ApprovedWithdrawnPepsin is approved by the FDA and is used in food at levels not to exceed current good manufacturing practice [L2363]. … Soon afterward, it was shown that these protein nutrients were cleaved by pepsin to products called _peptones_ [A32603].
Mixtures: Neo Life Enzyme Tab, Neo Life Beta Gest Tab