Search

Displaying results 7091 - 7100 of 10000 in total
  1. Target

    Endothelin-1 receptor

    go.drugbank.com/bio_entities/BE0000521
    TargetHumans

    Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3

    Synonyms: ET-A, Endothelin receptor type A
  2. Drug

    Methocarbamol

    go.drugbank.com/drugs/DB00423
    ApprovedInvestigationalVet approved

    [L6295] A combination product with [acetylsalicylic acid] and [codeine] is available in Canada by prescription.[L6295] Methocarbamol was FDA approved on 16 July 1957.[L6265] … [A178450] Methocarbamol tablets and intramuscular injections are prescription medicines indicated in the United States as an adjunct to rest, physical therapy, and other measures for the relief of discomforts

    Mixtures: SINAXAR ® A TABLETAS, SINAXAR ® A TABLETASSynonyms: (RS)-2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate
  3. Drug

    Ubrogepant

    go.drugbank.com/drugs/DB15328
    ApprovedInvestigational

    Ubrogepant is indicated for the acute treatment of migraine headaches with or without aura in adults. … [L10959] Several oral small molecule CGRP receptor antagonists, belonging to a class of medications referred to as "gepants", have been investigated for migraines, but only ubrogepant and [rimegepant]

    Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, P-glycoprotein substrates
  4. Indication

    Neoplasms

    go.drugbank.com/conditions/DBCOND0027948
    Drugs: Betamethasone phosphate · Prednisolone phosphate
    Synonyms: Malignant neoplasm without specification of site, [X]Malignant neoplasm without specification of site (disorder)
  5. Target

    HIV-1 retropepsin

    go.drugbank.com/bio_entities/BE0004854
    TargetHuman immunodeficiency virus 1

    Synonyms: Pepsin A
  6. Indication

    Fistulizing Crohn's Disease

    go.drugbank.com/conditions/DBCOND0058820
    Drugs: Infliximab
    Synonyms: Crohn's disease, unspecified, without complications
  7. Target

    Aspartate aminotransferase

    go.drugbank.com/bio_entities/BE0001217
    TargetEscherichia coli (strain K12)

    Synonyms: Transaminase A
  8. Target

    Flavodoxin 1

    go.drugbank.com/bio_entities/BE0003038
    TargetEscherichia coli (strain K12)

    Low-potential electron donor to a number of redox enzymes (Potential). Involved in the reactivation of inactive cob(II)alamin in methionine synthase.

    Synonyms: Flavodoxin A
  9. Target

    Cell division protein ZipA

    go.drugbank.com/bio_entities/BE0004000
    TargetEscherichia coli (strain K12)

    Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring (PubMed:11847116, PubMed:22164258, PubMed:22304478

    Synonyms: FtsZ interacting protein A
  10. Pathway

    De Novo Triacylglycerol Biosynthesis TG(a-21:0/a-13:0/i-12:0)

    smpdb.ca/view/SMP0038259
    Metabolic

    A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. … Last, the enzyme diacylglycerol O-acyltransferase synthesizes triacylglycerol from diacylglycerol and a fatty acyl-CoA.

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate