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Nilutamide
go.drugbank.com/drugs/DB00665ApprovedInvestigationalNilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors).
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 5,5-Dimethyl-3-(α,α,α-trifluoro-4-nitro-m-tolyl)hydantoinAprepitant
go.drugbank.com/drugs/DB00673ApprovedInvestigationalAprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. … Aprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting
Mixtures: LEMID® 125/80, LEMID® 125/80Categories: Substance P/Neurokinin-1 Receptor Antagonist, Neurokinin 1 AntagonistsIsoflurophate
go.drugbank.com/drugs/DB00677ApprovedWithdrawnIt is a powerful miotic used mainly in the treatment of glaucoma. Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically.
Synonyms: O,O'-diisopropyl phosphoryl fluorideTobramycin
go.drugbank.com/drugs/DB00684ApprovedInvestigationalsuch as β-lactams and cephalosporins. … [A232294, A232299, L32739] However, tobramycin can also be administered intravenously and topically to treat a variety of infections caused by susceptible bacteria.
Mixtures: TOBRAMISOL D®, GOTABIOTIC(R)F OFTALMICOCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexNicergoline
go.drugbank.com/drugs/DB00699ApprovedAn ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease.
Categories: Cytochrome P-450 Substrates, Adrenergic alpha-1 Receptor AntagonistsSynonyms: (8β)-10-methoxy-1,6-dimethylergoline-8-methanol 5-bromo-3-pyridinecarboxylate (ester), 10-methoxy-1,6-dimethylergoline-8β-methanol 5-bromonicotinateHomatropine methylbromide
go.drugbank.com/drugs/DB00725ApprovedHomatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics.
Mixtures: Debiline H, BONESPAS® TABLETASSynonyms: 3-alpha-Hydroxy-8-methyl-1-alpha-H,5-alpha-H-tropanium bromide mandelate, 8-Methylhomatropinium bromideNateglinide
go.drugbank.com/drugs/DB00731ApprovedApproximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight. … It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesOlive oil
go.drugbank.com/drugs/DB09567ApprovedInvestigationalUsed as a source of fatty acids in total parenteral nutrition and as an additive in some cosmetic products [FDA Label].
Mixtures: aspen nutrition Omega 3-6-9, Numeta G 13 % E Emulsion zur InfusionProducts: MediORO WApitegromab
go.drugbank.com/drugs/DB16096InvestigationalApitegromab is under investigation in clinical trial NCT03921528 (An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy).
Synonyms: Immunoglobulin g4 (234-proline), anti-(human progrowth differentiation factor 8) (human monoclonal srk-015 .gamma.4-chain), disulfide with human monoclonal srk-015 .lambda.-chain, dimer