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Alipogene tiparvovec
go.drugbank.com/drugs/DB13521ApprovedAlipogene tiparvovec is an adeno-associated viral vector of serotype 1-based gene therapy that delivers the Ser(447)X variant of the human lipoprotein lipase (LPL) gene.
Methoxy arachidonyl fluorophosphonate
go.drugbank.com/drugs/DB02465ExperimentalIt inhibits phospholipase A2 and fatty acid amide hydrolase with special potency, displaying IC50 values in the low-nanomolar range. … Methoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases.
Diprenorphine
go.drugbank.com/drugs/DB01548IllicitInvestigationalVet approvedA narcotic antagonist similar in action to naloxone. It is used to remobilize animals after etorphine neuroleptanalgesia and is considered a specific antagonist to etorphine. [PubChem]
Sonepcizumab
go.drugbank.com/drugs/DB06305InvestigationalUpon administration, sonepcizumab binds S1P, which may result in the inhibition of tumor angiogenesis. … S1P is the extracellular ligand for the G protein-coupled lysophospholipid receptor EDG-1 (endothelial differentiation gene-1).
OSI-7904L
go.drugbank.com/drugs/DB05457InvestigationalOSI-7904L is a liposome encapsulated thymidylate synthase inhibitor, which is indicated for use in advanced gastric and/or gastroesophageal adenocarcinoma (A-G/GEJA).
Multipotent adult arogenitor cells
go.drugbank.com/drugs/DB15742InvestigationalMultiStem is an intravenously-administered, off-the-shelf proprietary product developed which comprises Multipotent Adult Progenitor Cells (MAPCs). … The cells for creation of the product are isolated from a qualified donor and expanded on a large scale and then frozen until use. After administration, the cells are cleared from the body over time.
Pentaglobin
go.drugbank.com/drugs/DB15865Investigational[A220173] It is comprised of [immunoglobulin G (IgG)](https://www.drugbank.ca/drugs/DB00028) and immunoglobulin A (IgA) while also being enriched by immunoglobulin M (IgM).[L16353]
Recombinant Human Thrombopoietin
go.drugbank.com/drugs/DB16364Investigational[A225691, A225696] This drug is used in the treatment of thrombocytopenia.