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Displaying results 7131 - 7140 of 10000 in total
  1. Drug

    Norflurane

    go.drugbank.com/drugs/DB13116
    ApprovedInvestigationalWithdrawn

    Norflurane is under investigation in clinical trial NCT01673061 (Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage).

  2. Drug

    PR-104

    go.drugbank.com/drugs/DB05968
    Investigational

  3. Target

    B-cell receptor CD22

    go.drugbank.com/bio_entities/BE0000183
    TargetHumans

    Can also bind to ligands on other cells as an adhesion molecule in a trans configuration (PubMed:20172905). … Binds to alpha 2,6-linked sialic acid residues of surface molecules such as CD22 itself, CD45 and IgM in a cis configuration.

    Synonyms: BL-CAM
  4. Drug

    KBP-COVID-19

    go.drugbank.com/drugs/DB15858
    Investigational

    KBP cloned COVID-19’s genetic sequence, identified a potential antigen, and then inserted it into tobacco plants for reproduction. … Upon harvest, the antigens were purified, and these components underwent preclinical testing in animals.

  5. Drug

    Apazunersen

    go.drugbank.com/drugs/DB16981
    Investigational

    Apazunersen is an antisense oligonucleotide designed to target and inhibit the expression of UBE3A-AS. It is being investigated for the treatment of Angelman Syndrome.[L46772]

  6. Drug

    AVR-RD-02

    go.drugbank.com/drugs/DB17650
    Investigational

    AVR-RD-02 is an investigational _ex vivo_ lentiviral gene therapy developed by AVROBIO Inc. … AVR-RD-02 is being investigated in Gaucher Disease.[L45958]

  7. Drug

    SOR-C13

    go.drugbank.com/drugs/DB15366
    Investigational

    SOR-C13 is under investigation in clinical trial NCT01578564 (Safety and Tolerability Study of SOR-C13 in Subjects With Advanced Cancers Commonly Known to Express the TRPV6 Channel).

    Categories: Amino Acids, Peptides, and Proteins, Calcium-Regulating Hormones and Agents
  8. Drug

    Prinomastat

    go.drugbank.com/drugs/DB05100
    Investigational

    Prinomastat inhibits matrix metalloproteinases (MMPs) (specifically, MMP-2, 9, 13, and 14), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and … Prinomastat is a synthetic hydroxamic acid derivative with potential antineoplastic activity.

  9. Drug

    SAR445136

    go.drugbank.com/drugs/DB17708
    Investigational

    SAR445136 is an investigational zinc finger nuclease gene-edited cell therapy. … [A259063] It was formerly investigated for the treatment of beta-thalassemia, and it is currently being investigated for the treatment of sickle cell disease.[L46148]

  10. Drug

    D-Serine

    go.drugbank.com/drugs/DB03929
    ApprovedInvestigationalWithdrawn

    A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.