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Displaying results 7141 - 7150 of 10000 in total
  1. Drug

    E59

    go.drugbank.com/drugs/DB18372
    Experimental

    E59 is a humanized IgG1 low affinity allergic reactivity inhibiting (LARI) monoclonal antibody. It was developed by Sixal Inc.

  2. Drug

    Clevudine

    go.drugbank.com/drugs/DB06683
    Investigational

    Categories: Nucleic Acids, Nucleotides, and Nucleosides, Nucleoside and Nucleotide Reverse Transcriptase Inhibitors
  3. Drug

    KF-0210

    go.drugbank.com/drugs/DB17476
    Investigational

    KF-0210 is a small molecule developed by Keythera Pharmaceuticals. It is being investigated for cancers.

  4. Drug

    ONT-093

    go.drugbank.com/drugs/DB14069
    Experimental

    ONT-093 is an orally bioavailable inhibitor of P-glycoprotein (P-gp). … In pre-clinical studies, ONT-093 could inhibit P-gp and reverse multidrug resistance at nM concentrations with no effect on paclitaxel pharmacokinetics.

  5. Drug

    Oxfenicine

    go.drugbank.com/drugs/DB04291
    Experimental

    Oxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA).

    Categories: Amino Acids, Peptides, and Proteins
  6. Drug

    Nelipepimut-S

    go.drugbank.com/drugs/DB06226
    Investigational

    Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and Proteins
  7. Drug

    humanized SMART Anti-IL-12 Antibody

    go.drugbank.com/drugs/DB05848
    Experimental

    The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases. … IL-12 is a cytokine that may have considerable potential as a target in the therapy of autoimmune diseases.

    Synonyms: humanized SMART Anti-IL-12 Antibody
  8. Drug

    MCC

    go.drugbank.com/drugs/DB05282
    Investigational

    MCC has been shown to have immune stimulatory and apoptosis (programmed cell death) activity against cancer cells. The product is a sterile biological composition in a sub-micron suspension. … It is produced at the Bioniche manufacturing facility in Pointe-Claire, Quebec.

  9. Drug

    MLN576

    go.drugbank.com/drugs/DB06517
    Experimental

    XR11576 (MLN576) is a novel monophenazine with a mechanism of action that includes interaction with both topoisomerase (Topo) I and II.[A234609]

    Categories: Topoisomerase I Inhibitors, Topoisomerase II Inhibitors
  10. Drug

    Colforsin

    go.drugbank.com/drugs/DB02587
    Investigational

    Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland … Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii.

    Synonyms: 7β-acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-oneCategories: Compounds used in a research, industrial, or household setting