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J147
go.drugbank.com/drugs/DB13957ExperimentalJ147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. … [A31606,A31607,A31608] It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate initially developed for the treatment of neurodegenerative conditions associated with aging
Synonyms: N-(2,4-Dimethylphenyl)-2,2,2-trifluoro-N'-[(E)-(3-methoxyphenyl)methylene]acetohydrazideQuaternium-18
go.drugbank.com/drugs/DB11305ApprovedWithdrawnAcute oral and percutaneous toxicity tests in animals indicate that they exhibit little or no systemic toxic effects. … Quaternium-18 is a mixture of quaternary ammonium chloride salts. Quaternium-18 Hectorite and Bentonite are the reaction products of Quaternium-18 with clays.
XL281
go.drugbank.com/drugs/DB05190InvestigationalMutational activation of RAS occurs in about 30 percent of all human tumors, including non-small cell lung, pancreatic, and colon cancer. … XL281 is a specific inhibitor of RAF kinases, including the mutant form of B-RAF, which is activated in 60 percent of melanomas, 24-44 percent of thyroid cancers, and 9 percent of colon cancers.
Flurbiprofen axetil
go.drugbank.com/drugs/DB14938InvestigationalFlurbiprofen axetil is under investigation in clinical trial NCT02043366 (Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients).
Oftasceine
go.drugbank.com/drugs/DB11184ApprovedOftasceine is also referred to as Fluorexon. It is used in ophthalmic solutions as a staining agent when fitting soft and hard lenses. It is a fluorescent dye or luminescent agent.
PIKA rabies vaccine
go.drugbank.com/drugs/DB17963InvestigationalPIKA rabies vaccine is a novel vaccine developed by YS Biopharma.
SN-38
go.drugbank.com/drugs/DB05482InvestigationalSN 38 has been used in trials studying the treatment of Cancer, Advanced Solid Tumors, Small Cell Lung Cancer, Metastatic Colorectal Cancer, and Triple Negative Breast Cancer, among others. … 7-ethyl-10-hydroxycamptothecin (SN 38) is a liposomal formulation of the active metabolite of Irinotecan [DB00762], a chemotherapeutic pro-drug approved for the treatment of advanced colorectal cancer
Categories: Topoisomerase I InhibitorsMinzasolmin
go.drugbank.com/drugs/DB18961InvestigationalMinzasolmin is under investigation in clinical trial NCT05543252 (An Extension Study to Evaluate the Long-term Efficacy, Safety and Tolerability of Minzasolmin (UCB0599) in Study Participants With Parkinson's
Vasomera
go.drugbank.com/drugs/DB16498InvestigationalCategories: Amino Acids, Peptides, and Proteins, Hormones, Hormone Substitutes, and Hormone Antagonists