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Displaying results 711 - 720 of 8412 in total
  1. Drug

    Abrocitinib

    go.drugbank.com/drugs/DB14973
    ApprovedInvestigational

    JAK inhibitors recently attracted more attention as potential treatments for inflammatory disorders, as JAK inhibition is associated with rapid and sustained anti-inflammatory efects. … Abrocitinib is an oral small-molecule inhibitor of Janus kinase 1 (JAK1).

    Synonyms: PF-04965842Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
  2. Drug

    Fluoxetine

    go.drugbank.com/drugs/DB00472
    ApprovedInvestigationalVet approved

    Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI). It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly pre...

    Synonyms: (+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-P-tolyl)oxy)propylamineCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  3. Drug

    Sertraline

    go.drugbank.com/drugs/DB01104
    ApprovedInvestigational

    Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in th...

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: Van-sertraline, Ag-sertraline
  4. Drug

    Ancestim

    go.drugbank.com/drugs/DB09103
    ApprovedWithdrawn

    It is a 166 amino acid protein produced by E. coli with an amino acid sequence that is identical to the natural sequence predicted from human DNA sequence analysis, except for the addition of an N-terminal

  5. Drug

    LTI-03

    go.drugbank.com/drugs/DB18491
    Investigational

    LTI-03 is a caveolin-1 Scaffolding Domain 7-Mer

    Synonyms: Phe-thr-thr-phe-thr-val-thr
  6. Drug

    AOD9604

    go.drugbank.com/drugs/DB06388
    Experimental

    AOD9604 is a synthetic analogue of the lipolytic domain of human growth hormone, being investigated for the treatment of obesity.

    Synonyms: TYR-LEU-ARG-ILE-VAL-GLN-CYS-ARG-SER-VAL-GLU-GLY-SER-CYS-GLY-PHE CYCLIC (7->14)-DISULFIDE
  7. Drug

    Testosterone propionate

    go.drugbank.com/drugs/DB01420
    ApprovedInvestigationalVet approvedWithdrawn

    Currently, this drug has been discontinued in humans, but the vet application is still available as an OTC.[L1160]

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  8. Drug

    Adalimumab

    go.drugbank.com/drugs/DB00051
    ApprovedInvestigational

    Adalimumab is a subcutaneously administered biological disease modifier for the treatment of rheumatoid arthritis and other chronic debilitating diseases mediated by tumor necrosis factor. It was originally launched by Abbvie in the U.S....

    Products: HUMIRA SOLUTION FOR INJECTION 40MG/0.8ML (VIAL), IDACIO SOLUTION FOR INJECTION FOR PAEDIATRIC USE 40MG/0.8ML VIAL
  9. Drug

    Aluminum chlorohydrate

    go.drugbank.com/drugs/DB11573
    Approved

    It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent.

    Mixtures: Ban Ultra Antiperspirant Roll-ONProducts: Jardins Du Monde Antisudorifique A Bille, Jardins du Monde Indian Cotton Flower Antiperspirant Roll-On
  10. Drug

    Polyethylene glycol

    go.drugbank.com/drugs/DB09287
    ApprovedInvestigationalVet approved

    [A190975] Molecular weights of PEGs vary by time of the polymerization process and the molecular weight represents the weighted average of the individual PEG molecules. … [L6421] The rationale of using PEG in gastroenterology is due to the physical properties of the compound: its potent water-binding capacity, negligible intestinal absorption with increasing molecular

    Categories: P-glycoprotein inhibitorsProducts: MACRO P, Dg Health Clearlax