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Asparaginase Erwinia chrysanthemi
go.drugbank.com/drugs/DB08886ApprovedInvestigationalAsparaginase Erwinia chrysanthemi is an asparaginase-specific enzyme derived from Erwinia chrysanthemi used as an anticancer agent. It works by depleting the stores of an important amino acid called asparagine, which is involved in DNA s...
Neomycin
go.drugbank.com/drugs/DB00994ApprovedInvestigationalVet approvedNeomycin is a broad-spectrum aminoglycoside antibiotic drug that is derived from the metabolic products of Streptomyces fradiae. Neomycin is a complex comprised of three components, neomycin A, B, and C. Neomycin B, also known as framyce...
Mixtures: Up and Up Antibiotic, Up and Up AntibioticBaricitinib
go.drugbank.com/drugs/DB11817ApprovedInvestigationalBaricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthrit...
Nerandomilast
go.drugbank.com/drugs/DB18237ApprovedInvestigational[A274581] On December 19, 2025, the U.S. FDA approved nerandomilast tablets for the treatment of progressive pulmonary fibrosis (PPF) in adults.
Hepatitis A Vaccine
go.drugbank.com/drugs/DB10989ApprovedInvestigational[A199185,L12756] In the US, the approved vaccine is inactivated while live Hepatitis A vaccines are currently available in other countries.[L13392]
Ataluren
go.drugbank.com/drugs/DB05016ApprovedWithdrawnThis drug does not yet have approval by the US Food and Drug Administration or by Health Canada for any indications.
Chlormadinone acetate
go.drugbank.com/drugs/DB15903ApprovedWithdrawnIn the US, chlormadinone acetate was formerly marketed as a component of the combination drug products Estalor-21 and C-Quens.
Autologous cultured chondrocytes
go.drugbank.com/drugs/DB10997ApprovedInvestigationalThe surgical implantation shows a tolerable safety profile and efficacy up to 4 years, but it is not indicated for patients with osteoarthritis.
Zongertinib
go.drugbank.com/drugs/DB18762ApprovedInvestigational[L53873,A274363] On August 8, 2025, the US FDA granted accelerated approval to zongertinib for the treatment of advanced forms of non-small cell lung cancer (NSCLC) with HER2 tyrosine kinase domain
Asfotase alfa
go.drugbank.com/drugs/DB09105ApprovedInvestigationalalfa was first approved by Pharmaceuticals and Medicals Devices Agency of Japan (PMDA) on July 3, 2015, then approved by the European Medicine Agency (EMA) on August 28, 2015, and was approved by the U.S