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Zavacorilant
go.drugbank.com/drugs/DB21509InvestigationalThe usage of the INN stem '-corilant' in the name indicates that Zavacorilant is a glucocorticoid receptor antagonist (non-steroidal).
2-hydroxy-7-methoxy-5-methyl-naphthalene-1-carboxylic acid meso-2,5-dihydroxy-cyclopent-3-enyl ester
go.drugbank.com/drugs/DB08261ExperimentalThis compound belongs to the naphthalenecarboxylic acids and derivatives. These are compounds containing a napthalene moiety with a ring carbon which bears a carboxylic acid group or a derivative.
Aptazapine
go.drugbank.com/drugs/DB09305ExperimentalIt antagonised α2 adrenergic receptors approximately 10 times more effectively than mianserin, antagonised 5-HT2 receptors, agonised H1 receptors, and did not affect reuptake of serotonin or norepinephrine
Isometheptene
go.drugbank.com/drugs/DB06706ApprovedIsometheptene is a sympathomimetic drug that causes vasoconstriction. It is used for treating migraines and tension headaches.
Casdatifan
go.drugbank.com/drugs/DB21701InvestigationalCasdatifan is under investigation in clinical trial NCT07000149 (A Study to Investigate the Efficacy and Safety of Volrustomig ± Casdatifan vs Nivolumab + Ipilimumab as 1L Treatment for Advanced ccRCC)
Tegtociclib
go.drugbank.com/drugs/DB21635InvestigationalTegtociclib is under investigation in clinical trial NCT05262400 (A Study to Learn About the Study Medicine (Called PF-07220060 in Combination With PF-07104091) In Participants With Breast Cancer and Solid
Nicomorphine
go.drugbank.com/drugs/DB13454ExperimentalCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeTandospirone
go.drugbank.com/drugs/DB12833InvestigationalTandospirone has been used in trials studying the treatment of Schizophrenia.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndromeα-Methylacetylfentanyl
go.drugbank.com/drugs/DB01532ExperimentalIllicitIt was categorized under the Schedule I in the US and it was illegally sold in early 1980. α-Methylacetylfentanyl synthesis process is very similar to α-methylfentanyl with the substitution of the acetic