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Displaying results 7201 - 7210 of 10000 in total
  1. Drug

    Indoprofen

    go.drugbank.com/drugs/DB08951
    ApprovedWithdrawn

    A drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.

    Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 2-Ring
  2. Drug

    Dimenoxadol

    go.drugbank.com/drugs/DB01461
    ExperimentalIllicit

    In the United States it is classified as a Schedule I controlled drug. … Dimenoxadol is an opioid analgesic which produces typical opioid effects such as analgesia and sedation. It is structurally similar to methadone and is a benzilic acid derivative.

  3. Drug

    Frespaciguat

    go.drugbank.com/drugs/DB21683
    Investigational

    Frespaciguat is a small molecule drug. The usage of the INN stem '-ciguat' in the name indicates that Frespaciguat is a guanylate cyclase activator and stimulator. … Frespaciguat is under investigation in clinical trial NCT05612035 (Frespaciguat (MK-5475) INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of Frespaciguat (an Inhaled sGC Stimulator) in Adults With

  4. Drug

    Trefentanil

    go.drugbank.com/drugs/DB09181
    Experimental

    Trefentanil (A-3665) is a fentanyl analogue opioid developed in 1992. It is more potent and shorter acting than alfentanil. … Trefentanil is not used in clinics due to the severity of its respiratory depression, though it is still used in research.

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Emfilermin

    go.drugbank.com/drugs/DB06562
    Investigational

  6. Drug

    Fibroblast growth factor-1

    go.drugbank.com/drugs/DB05599
    Investigational

    Synonyms: Fibroblast growth factor-1Mixtures: Le-Blen FGF Serum
  7. Drug

    CTCE-9908

    go.drugbank.com/drugs/DB05625
    Investigational

    Synonyms: L-Lysinamide,N2,N6-bis(L-lysylglycyl-L-valyl-L-seryl-L-leucyl-L-seryl-L-tyrosyl-L-arginyl)-, SDF-1 (108) Lysine Dlmer
  8. Drug

    Isatoribine

    go.drugbank.com/drugs/DB04860
    Experimental

    Isatoribine is a selective agonist of TLR7.

    Synonyms: 7-Deaza-7-thia-8-oxoguanosine, 7-Thia-8-oxoguanosineCategories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Tranilast

    go.drugbank.com/drugs/DB07615
    Investigational

    Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. In 1982, it was approved in Japan and South Korea for the management of bronchial asthma. … Indications for keloid and hypertrophic scar were added in 1993. It has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.

    Synonyms: N-(3,4-Dimethoxycinnamoyl)anthranilic acidCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    AZD0947

    go.drugbank.com/drugs/DB04848
    Experimental

    As of March 2003, the drug was in phase II trials; however, as of October 2004, it no longer appeared on the company’s development pipeline. … AZD0947 is a K+ channel opener, which was under investigation by AstraZeneca for the treatment of overactive bladder.