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R411
go.drugbank.com/drugs/DB05468ExperimentalIt is not immunosuppressive, but blocks the activation and recruitment of cells involved in respiratory inflammation. … It is a dual-acting competitive integrin antagonist (as compared to previously developed single integrin antagonists or SIAs) that prevents binding of V-CAM1 to either a4b1 or a4b7.
Vicasinabin
go.drugbank.com/drugs/DB21587InvestigationalVicasinabin has a monoisotopic molecular weight of 358.2 Da. … Vicasinabin is under investigation in clinical trial NCT04265261 (A Study to Investigate the Efficacy and Safety of RG7774 in Patients With Diabetes Mellitus Type 1 or Type 2 With Treatment-Naive Diabetic
Amobarbital
go.drugbank.com/drugs/DB01351ApprovedIllicit(From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
Carafiban
go.drugbank.com/drugs/DB19813ExperimentalCarafiban has a monoisotopic molecular weight of 465.2 Da. … The usage of the INN stem '-fiban' in the name indicates that Carafiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Licostinel
go.drugbank.com/drugs/DB19864ExperimentalThe usage of the INN stem '-stinel' in the name indicates that Licostinel is a N-methyl-D-aspartate (NMDA) receptor co-agonist. Licostinel has a monoisotopic molecular weight of 274.95 Da.
Evifacotrep
go.drugbank.com/drugs/DB21510InvestigationalEvifacotrep has a monoisotopic molecular weight of 441.06 Da. … The usage of the INN stem '-cotrep' in the name indicates that Evifacotrep is a transient receptor potential canonical channel 5 (TRPC5) antagonist.
Orbofiban
go.drugbank.com/drugs/DB20676ExperimentalOrbofiban has a monoisotopic molecular weight of 361.18 Da. … The usage of the INN stem '-fiban' in the name indicates that Orbofiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Gantofiban
go.drugbank.com/drugs/DB20951ExperimentalGantofiban has a monoisotopic molecular weight of 447.21 Da. … The usage of the INN stem '-fiban' in the name indicates that Gantofiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Roxifiban
go.drugbank.com/drugs/DB21089ExperimentalRoxifiban has a monoisotopic molecular weight of 447.21 Da. … The usage of the INN stem '-fiban' in the name indicates that Roxifiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).
Sibrafiban
go.drugbank.com/drugs/DB21420ExperimentalSibrafiban has a monoisotopic molecular weight of 420.2 Da. … The usage of the INN stem '-fiban' in the name indicates that Sibrafiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).