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D-JNKI-1
go.drugbank.com/drugs/DB05660InvestigationalA synthetic, cell permeable peptide that blocks the MAPK-JNK signal pathway; has potential therapeutic value for long-term protection of both the morphological integrity and physiological function of the organ of Corti during times of ox...
Botulinum toxin type B
go.drugbank.com/drugs/DB00042ApprovedThe protein exists in noncovalent association with hemagglutinin and nonhemagglutinin proteins as a neurotoxin complex.
Cilobradine
go.drugbank.com/drugs/DB20039InvestigationalCilobradine is under investigation in clinical trial NCT02264041 (Effect of Cytochrome P 450 3A4 Inhibition by Itraconazole on the Single Oral Dose Pharmacokinetics of Cilobradine). … The usage of the INN stem '-bradine' in the name indicates that Cilobradine is a bradycardic agent.
Resomelagon
go.drugbank.com/drugs/DB21579InvestigationalResomelagon is under investigation in clinical trial NCT06917001 (Clinical Trial Evaluating Safety and Efficacy of Resomelagon on Dengue Infection (RESOVIR-2)). … The usage of the INN stem '-melagon' in the name indicates that Resomelagon is a non-peptidic melanocortin receptor agonist.
Melengestrol
go.drugbank.com/drugs/DB11529ExperimentalVet approvedAn acylated derivative, melengestrol acetate, is used as a growth promoter in animals.
BMS-919373
go.drugbank.com/drugs/DB15047InvestigationalBMS-919373 is under investigation in clinical trial NCT02153437 (Study of the Effects of BMS-919373 on the Electrical Activity of the Heart Using Pacemakers).
Iratumumab
go.drugbank.com/drugs/DB05550InvestigationalIn phase I/II clinical trials for treatment of CD30+ lymphomas.
MLN2222
go.drugbank.com/drugs/DB06503ExperimentalMLN2222 is a novel, proprietary recombinant protein that blocks both the C3 and C5 convertases, which are essential components of the complement activation pathway.
V24343
go.drugbank.com/drugs/DB05201InvestigationalThe anti-obesity drug, V24343, acts by targeting the CB1 receptor in the brain and suppressing a person's appetite.
RDP58
go.drugbank.com/drugs/DB06566ExperimentalRDP58 (NH2-arg-norleucine (nle)-nle-arg-nle-nle-nle-gly-tyr-CONH2) (Sangstat Corp., Fremont, California) is a novel synthetic peptide that inhibits early signal transduction pathways for the expression of inflammatory cytokines.