Botulinum toxin type B is a purified form of botulinum toxin type B used to block acetylcholine release in the treatment of cervical dystonia and sialorrhea. Neurotoxin produced by fermentation of clostridium botulinum type B.
- Mechanism
- Curator reviewed
Botulinum Toxin Type B binds to and cleaves the synaptic Vesicle Associated Membrane Protein (VAMP, also known as synaptobrevin) which is a component of the protein complex responsible for docking and fusion of the synaptic vesicle to the presynaptic membrane, a necessary step to neurotransmitter release.
- Primary indication
- For the treatment of patients with cervical dystonia to reduce the severity of abnormal head position and neck pain associated with cervical dystonia.Curator reviewed · 2 structured indications
- Formula / weight
- 150804.0 Da
- First approval
- Canada, 2004 · United States, 2000
- Also known as
- Botulin B · Botulinum antitoxin type B · Botulinum B toxin · Botulinum neurotoxin type B precursor · BTX-B
- Code names
- AN-0772
- Brand names
Resolves to
What you can answer from here — as of October 01, 2026
Which drugs share a target with Botulinum toxin type B, and which of those have an active Phase 3 trial?
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