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Displaying results 721 - 730 of 10000 in total
  1. Drug

    Nabumetone

    go.drugbank.com/drugs/DB00461
    Approved

    [A179077] While slightly reduced, possibly due to a degree of cyclooxygenase-2 selectivity (COX-2), nabumetone still produces significant adverse effects in the GI tract. … [label,A178903] The molecule itself is a pro-drug with its 6-methoxy-2-naphthylacetic acid (6-MNA) metabolite acting as a potent COX inhibitor similar in structure to [naproxen].

    Mixtures: NuDroxiPAK N-500Products: Relafen DS
  2. Drug

    Carboxymethylcellulose

    go.drugbank.com/drugs/DB11059
    ApprovedInvestigational

    It is added in food products as a viscosity modifier or thickener and emulsifier. … It is also one of the most common viscous polymers used in artificial tears, and has shown to be effective in the treatment of aqueous tear-deficient dry eye symptoms and ocular surface staining [A33029

    Categories: Compounds used in a research, industrial, or household settingProducts: EyS-ED, CRISTALTEARS® 1% LC
  3. Drug

    Povidone

    go.drugbank.com/drugs/DB11061
    ApprovedInvestigationalWithdrawn

    [DB06812] can be found in over-the-counter topical solutions, ointment, pessaries, liquid soaps and surgical scrubs. … Povidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant

    Mixtures: DG Health Sterile Advanced Relief Eye, DG Health Advanced Relief Eye DropsCategories: Compounds used in a research, industrial, or household setting
  4. Drug

    Pipemidic acid

    go.drugbank.com/drugs/DB13823
    Investigational

    Pipemidic acid is a quinolone antibacterial agent with activity against various gram-positive and gram-negative bacteria.[A275138, A275143]

    Products: ACIDO PIPEMIDICO EG, ACIDO PIPEMIDICO DR. REDDY'S
  5. Drug

    Olanzapine

    go.drugbank.com/drugs/DB00334
    ApprovedInvestigational

    [A177011] Olanzapine was discovered by scientists at Eli Lilly and approved to be marketed in the US in 1996.[T548] … Olanzapine is a thienobenzodiazepine derivative and an atypical or second-generation antipsychotic agent.

    Categories: Dopamine D2 Receptor AntagonistsProducts: MARATHON D, OLANZAPINA DR. REDDY'S
  6. Pathway

    De Novo Triacylglycerol Biosynthesis

    smpdb.ca/view/SMP0015896
    Metabolic

    De novo biosynthesis of triglycerides is also known as the phosphatidic acid pathway, and it is mainly associated with the liver and adipose tissue.

    Drugs: NADH · Magnesium cation · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate
  7. Drug

    Ramipril

    go.drugbank.com/drugs/DB00178
    ApprovedInvestigational

    Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to reduce the rate of death, myocardial infarction and stroke in individuals at high risk of cardiovascular … Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys.

    Mixtures: RAMIPLUS AL 5MG/25MG, RAMIPLUS AL 5MG/25MGCategories: Agents Acting on the Renin-Angiotensin System
  8. Drug

    Ginger

    go.drugbank.com/drugs/DB10344
    ApprovedInvestigational

    Ginger allergenic extract is used in allergenic testing.

    Mixtures: C Ottways Lax TabProducts: Zinaxin Ev. Ext 77 Ginger Extract
  9. Drug

    Chloramphenicol

    go.drugbank.com/drugs/DB00446
    ApprovedInvestigationalVet approvedWithdrawn

    (From Martindale, The Extra Pharmacopoeia, 29th ed, p106) The FDA has withdrawn all oral drug products containing chloramphenicol, due to the high risk of fatal aplastic anemia associated with this … It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic.

    Synonyms: D-(−)-2,2-dichloro-N-(β-hydroxy-α-(hydroxymethyl)-p-nitrophenylethyl)acetamide, D-(−)-threo-1-p-nitrophenyl-2-dichloroacetylamino-1,3-propanediolProducts: PALMITATO DE CHLOROMYCETIN
  10. Drug

    Eszopiclone

    go.drugbank.com/drugs/DB00402
    ApprovedInvestigational

    Eszopiclone was initially approved by the FDA in 2004.[L6769] … Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic drug used to treat insomnia.

    International brands: Wen FeiProducts: DORMEBEN® EZ 2 MG TABLETAS RECUBIERTAS., DORMEBEN® EZ 3 MG TABLETAS RECUBIERTAS