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Displaying results 7301 - 7310 of 10000 in total
  1. Drug

    RGN6024

    go.drugbank.com/drugs/DB33059
    Experimental

    Preclinical characterization reports that RGN6024 binds the colchicine-binding site of beta-tubulin, inhibits microtubule polymerization in biochemical and cellular assays, induces G2/M arrest in glioblastoma … RGN6024, also known as RGN-6024 or RGNi6024, is a synthetic small-molecule tubulin destabilizer from Reglagene.

  2. Drug

    Pemoline

    go.drugbank.com/drugs/DB01230
    ApprovedIllicitWithdrawn

    In 2005, the Food and Drug Administration (FDA) withdrew approval for pemoline. In March 2005, Abbott Laboratories (Cylert marketer) had discontinued the production of Cylert arguing economic reasons.

    Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Methapyrilene

    go.drugbank.com/drugs/DB04819
    ApprovedWithdrawn

    Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: N-(α-pyridyl)-N-(α-thenyl)-N',N'-dimethylethylenediamine, N,N-dimethyl-N'-pyrid-2-yl-N'-2-thenylethylenediamine
  4. Drug

    Morus alba root bark

    go.drugbank.com/drugs/DB14271
    Investigational

    Morus alba root bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  5. Drug

    Magnolia kobus flowering top

    go.drugbank.com/drugs/DB14319
    Investigational

    Magnolia kobus flowering top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  6. Drug

    Zanthoxylum clava-herculis bark

    go.drugbank.com/drugs/DB14379
    Experimental

    Zanthoxylum clava-herculis bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  7. Drug

    Leriglitazone

    go.drugbank.com/drugs/DB15021
    Investigational

    Leriglitazone is under investigation in clinical trial NCT03917225 (A Clinical Study to Evaluate the Effect of MIN-102 on the Progression of Friedreich's Ataxia in Male and Female Patients).

    Synonyms: 2,4-thiazolidinedione, 5-((4-(2-(5-(1-hydroxyethyl)-2-pyridinyl)ethoxy)phenyl)methyl)-, All-ambo-5-((4-(2-(5-(1-hydroxyethyl)pyridin-2-yl)ethoxy)phenyl)methyl)-1,3-thiazole-2,4(3H,5H)-dioneCategories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Tenamfetamine

    go.drugbank.com/drugs/DB01509
    IllicitInvestigational

    An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. … It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally. [PubChem]

  9. Drug

    Aminoimidazole carboxamide

    go.drugbank.com/drugs/DB06143
    Investigational

    Synonyms: 5-Aminoimidazol-4-carboxamide, 5-Aminoimidazole-4-carboxamideCategories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Semaxanib

    go.drugbank.com/drugs/DB06436
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring