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ALM201
go.drugbank.com/drugs/DB17206InvestigationalALM201 is an anti-angiogenic synthetic peptide identified from the endogenous human protein, FKBPL. It is being investigated in the treatment of various cancers.[A254556]
ORE-1001
go.drugbank.com/drugs/DB12271InvestigationalORE1001 has been used in trials studying the treatment of Mild to Moderate Ulcerative Colitis. It is an ACE2 inhibitor.
Categories: Heterocyclic Compounds, 1-RingSTI-1499
go.drugbank.com/drugs/DB16487InvestigationalSTI-1499 (COVI-GUARD was under investigation in clinical trial NCT04454398 to evaluate its safety and efficacy in patients with moderate COVID-19.
Indopan
go.drugbank.com/drugs/DB01446ExperimentalIllicitIt was developed in the 1960's by Upjohn with the intention for use as an antidepressant. In the 1990's, indopan became regulated as a Schedule I controlled substance in the United states. … Indopan (alpha-methyltryptamine) is a stimulant and psychoactive drug which produces effects similar to 3,4-methylenedioxy-N-methylamphetamine (MDMA), despite being structurally dissimilar.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Heterocyclic Compounds, 2-RingSynonyms: 1-(1H-Indol-3-yl)-2-propanamine, 3-(2-Aminopropyl)indoleTAS-102
go.drugbank.com/drugs/DB08937InvestigationalTAS-102 (Taiho Pharma USA, Inc.) is an anti-cancer drug under development and in stage 3 clinical trials for the treatment of colorectal cancer. … It is composed of the thymidine phosphorylase inhibitor (TPI) tipiracil and the cytotoxin trifluridine. Trifluridine inhibits tumor growth by being incorporated into DNA during DNA synthesis.
Categories: Heterocyclic Compounds, 1-RingD-glyceraldehyde 3-phosphate
go.drugbank.com/drugs/DB02263ExperimentalAn aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis.
Synonyms: D-Glyceraldehyde 3-phosphate, (2R)-2-Hydroxy-3-(phosphonooxy)-propanalGSK-239512
go.drugbank.com/drugs/DB15120InvestigationalGSK-239512 is under investigation in clinical trial NCT00474513 (An Imaging Study to Investigate the Distribution of GSK239512 in the Brain.).
Categories: Heterocyclic Compounds, 2-RingFosmanogepix
go.drugbank.com/drugs/DB15183InvestigationalFosmanogepix is under investigation in clinical trial NCT03604705 (An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemia).
Synonyms: [2-amino-3-[3-[[4-(2-pyridyloxymethyl)phenyl]methyl]isoxazol-5-yl]pyridin-1-ium-1-yl]methyl hydrogen phosphateJosamycin
go.drugbank.com/drugs/DB01321InvestigationalA macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.
Synonyms: leucomycin V 3-acetate 4B-(3-methylbutanoate), leucomycin V 3-acetate 4β-(3-methylbutanoate)Products: Josalid 250 mg/5 ml - Saft für Kinder, Josalid 375 mg/5 ml - Saft für KinderDaledalin
go.drugbank.com/drugs/DB09189ExperimentalIt was in trials for depression in the 1970s but never marketed. … Daledin (UK-3557-15) is a selective norepinephrine reuptake inhibitor. It has no effects on the reuptake of serotonin or dopamine, and no antihistamine or anticholinergic properties.
Categories: Heterocyclic Compounds, 2-Ring