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Brimonidine
go.drugbank.com/drugs/DB00484ApprovedInvestigational[A178951] It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. … [A178969] The ophthalmic solution of brimonidine was first approved by the FDA in 1996 as Alphagan [label] and brimonidine is the only selective alpha-adrenergic receptor agonist approved for chronic treatment
Mixtures: SIMBRINZA 10mg/ml + 2mg/ml eye drops, suspension, COMBIGAN EYE DROPS (Brimonidine tartrate 2mg/ml and timolol 5mg/ml opthalmic solution)Categories: Sympathomimetics Used as DecongestantsMycophenolate mofetil
go.drugbank.com/drugs/DB00688ApprovedInvestigational[L7363] It is marketed by Roche Pharmaceuticals and was granted FDA approval for the prophylaxis of transplant rejection in 1995. … It demonstrates an increased bioavailability, a higher efficacy, and reduced gastrointestinal effects when compared to MPA.[A180826]
Synonyms: 2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoateProducts: MYFENAX 250MG, CELLCEPT 250MGAdenosine
go.drugbank.com/drugs/DB00640ApprovedInvestigational[A229828] Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy,[L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] … [L31998] Adenosine was granted FDA approval on 30 October 1989.[L31978]
Mixtures: Super Plus Beblesh Balm Triple Functions SPF50 Plus PA 3Plus (40g), Ginseng Royal Silk Eye 25mlProducts: ADOZIN 10MG/2ML IV ENJEKSIYON VE INFÜZYON IÇIN ÇÖZELTI IÇEREN AMPUL, 10 AMPUL, ADOZIN 50MG/10ML IV ENJEKSIYON VE INFÜZYON IÇIN ÇÖZELTI IÇEREN FLAKON, 10 FLAKONBuclizine
go.drugbank.com/drugs/DB00354ApprovedIt was manufactured by Stuart Pharms and initially approved by the FDA in 1957. … [L6217] Following this, it was touted to be effective as an appetite stimulant in children when administered in the syrup form, however, this indication has not been validated.
Products: BUCLIZINA CLORHIDRATO 25MGFormoterol
go.drugbank.com/drugs/DB00983ApprovedInvestigational[A189528] A major clinical advantage of formoterol over other inhaled beta-agonists is its rapid onset of action (2-3 minutes), which is at least as fast as [salbutamol], combined with a long duration … [L10986] It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers.
Mixtures: FLUTIFORM 250/10UG 120 HUB, FLUTIFORM 250/10UG 3X120HUProducts: FORMATRIS 6UG 100ED PAT, FORMATRIS 12UG 100ED PATTibolone
go.drugbank.com/drugs/DB09070ApprovedInvestigationalTibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha [L1874]. … It has been used in Europe for almost 2 decades, primarily for the prevention of postmenopausal osteoporosis and the treatment of post-menopausal symptoms [L1720].
Synonyms: 17-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-oneProducts: LIVIAL TABLET 2.5MG, TIBOLEEN 2.5MG TABLETSCabazitaxel
go.drugbank.com/drugs/DB06772ApprovedInvestigationalIt was first approved by the FDA on June 17, 2010.[A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17, 2019.[L47376] … [A260621] As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death.
Products: XITACAB® 60MG/1.5ML (40MG/ML), CABAZITAXEL EGTepotinib
go.drugbank.com/drugs/DB15133ApprovedInvestigational[A228058] It was originally developed in partnership between EMD Serono and the University of Texas M.D. … [A228058] MET is a desirable target in the treatment of certain solid tumors as it appears to play a critical role, both directly and indirectly, in the growth and proliferation of tumors in which it is
Categories: Proto-Oncogene Proteins c-met, antagonists & inhibitorsProducts: TEPMETKO FILM-COATED TABLET 225MGTemsirolimus
go.drugbank.com/drugs/DB06287ApprovedInvestigationalIt was developed by Wyeth Pharmaceuticals under the trade name Torisel. Temsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007.
Products: Torisel Concentrate for Injection 25mg/mLFlucloxacillin
go.drugbank.com/drugs/DB00301ApprovedInvestigationalWithdrawnAntibiotic analog of cloxacillin.
Products: Fluclox-125 Pws 125mg/5ml, Fluclox-250 Cap 250mg