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Displaying results 731 - 740 of 5504 in total

Drug
Burosumab
go.drugbank.com/drugs/DB14012
ApprovedInvestigational
It causes impaired bone growth and development in children and adolescents and issues with bone mineralization throughout a patient’s life [L2346].
Products: CRYSVITA ® SOLUCION PARA INYECCIÓN 10MG/ML
Drug
Metocurine iodide
go.drugbank.com/drugs/DB00416
ApprovedWithdrawn
It is used as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy Metocurine iodide has a moderate risk of inducing histamine
Products: Metubine Iodide Inj 2mg/ml
Drug
Alectinib
go.drugbank.com/drugs/DB11363
ApprovedInvestigational
It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) fusion protein that causes proliferation of NSCLC
Products: ALECENSA HARD CAPSULE 150MG, Alecensa (Alectinib) Hard Capsules 150mg
Drug
Mefloquine
go.drugbank.com/drugs/DB00358
Approved
It was approved by the FDA in 1989, and was first marketed by Hoffman Laroche. … Individuals at the highest risk for malaria are those in disease naïve populations, children under age 5, refugees in Central and Eastern Africa, nonimmune civilian and military travelers, pregnant women
Products: Lariam Tab 250mg
Drug
Asunaprevir
go.drugbank.com/drugs/DB11586
ApprovedWithdrawn
It has been shown to have a very high efficacy in dual-combination regimens with daclatasvir in patients chronically infected with HCV genotype 1b. … [A32528] It was developed by Bristol-Myers Squibb Canada and approved by Health Canada on April 22, 2016. The commercialization of asunaprevir was cancelled one year later on October 16, 2017.[L1113]
Products: SUNVEPRA CAPSULE 100MG, SUNVEPRA® 100MG CÁPSULAS BLANDAS
Drug
Doconexent
go.drugbank.com/drugs/DB03756
ApprovedInvestigational
It can be biosythesized from alpha-linolenic acid or commercially manufactured from microalgae. … It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin, and retina thus plays an important role in their development and function.
Mixtures: Live-well™ Toco-E CapsuleProducts: Nova Neurogel DHA 250mg Softgel Capsule
Drug
Guselkumab
go.drugbank.com/drugs/DB11834
ApprovedInvestigational
IL-23 is an inflammatory cytokine that activates the CD4+ T-helper (Th17) cell pathway to mediate the inflammatory cascade that induces psoriatic plaque formation [A20357].
Products: TREMFYA 100MG/ML SOLUTION FOR INJECTION, Tremfya One-Press 100mg/ml Solution for Injection
Drug
Clenbuterol
go.drugbank.com/drugs/DB01407
ApprovedInvestigationalVet approved
A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
Mixtures: SEKRETOVIT EX, MUCOSOLVAN®COMPOSITUM GOTAS 15MG/0.01MG/2MLProducts: CLENBUTEROL 10MCG/5ML
Drug
Remdesivir
go.drugbank.com/drugs/DB14761
ApprovedInvestigational
[A191379, A222393] Broad antiviral activity of remdesivir is suggested by its mechanism of action,[A222398] and to date, it has demonstrated _in vitro_ activity against the _Arenaviridae_, _Flaviviridae
Products: COVIFOR (REMDESIVIR FOR INJECTION 100MG/VIAL), VEKLURY® LYOPHILIZED POWDER FOR IV INFUSION 100MG/VIAL
Drug
Exenatide
go.drugbank.com/drugs/DB01276
ApprovedInvestigational
It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control[L42690]. … It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand name product of extended-release exenatide in an injectable suspension, was discontinued in 2021.
Products: BYDUREON® BCISE® 2MG SUSPENSIÓN DE LIBERACIÓN PROLONGADA, BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG