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AI-128
go.drugbank.com/drugs/DB05841ExperimentalAI-128 is the first human demonstration of sustained release drug administration in the lung. … AI-128 consists of slowly dissolving microspheres designed to control where drug particles go in the lung and how quickly they release their drug.
Bufotenine
go.drugbank.com/drugs/DB01445ExperimentalIllicitBufotenin has been used as a tool in CNS studies and misused as a psychedelic. … A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics.
Categories: Monoamine Oxidase A SubstratesRisuteganib
go.drugbank.com/drugs/DB14911InvestigationalRisuteganib is under investigation in clinical trial NCT02348918 (Phase 2 Randomized Clinical Trial of Luminate® as Compared to Avastin® in the Treatment of Diabetic Macular Edema).
MaxAdFVIII
go.drugbank.com/drugs/DB17713ExperimentalMaxAdFVIII is an adenoviral vector that expresses the full-length human Factor VIII (hFVIII) cDNA. First developed by GenStar, it is being investigated for the treatment of hemophilia.
UM-171
go.drugbank.com/drugs/DB19449InvestigationalUM-171 is a pyrimidoindole derivative that is an agonist of ex vivo hematopoietic stem cell expansion and thus supports the expansion of hematopoietic stem cells.[A264868, A264873]
Rebaudioside A
go.drugbank.com/drugs/DB15136InvestigationalRebaudioside A is under investigation in clinical trial NCT03510624 (Acute Effect of Rebaudioside A on Glucose Excursion During an Oral Glucose Tolerance Test in Type 2 Diabetes Mellitus).
Synonyms: Rebaudioside AOntamalimab
go.drugbank.com/drugs/DB15298InvestigationalOntamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307)).
Macelignan
go.drugbank.com/drugs/DB14129InvestigationalMacelignan is an NSAID with antioxidant, free radical scavenging, and neuroprotective activities.
Go-6976
go.drugbank.com/drugs/DB17029ExperimentalAn inhibitor of calcium-dependent isoforms of protein kinase C.[A253002,A253007]
Synonyms: 12h-indolo(2,3-a)pyrrolo(3,4-c)carbazole-12-propanenitrile, 5,6,7,13-tetrahydro-13-methyl-5-oxo-N-oleoyldopamine
go.drugbank.com/drugs/DB17036ExperimentalN-oleoyldopamine (OLDA) is an amide of dopamine and oleic acid.[A253042]