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Displaying results 7441 - 7450 of 10000 in total
  1. Drug

    R112

    go.drugbank.com/drugs/DB06252
    Experimental

    R112 is an investigational compound developed to treat Allergic Rhinitis. It's mechanism of action is to inhibit SYK kinase.

    Synonyms: 3-((5-FLUORO-2-(3-HYDROXYANILINO)PYRIMIDIN-4-YL)AMINO)PHENOL, 3,3'-((5-FLUORO-2,4-PYRIMIDINEDIYL)DIIMINO)BIS(PHENOL)
  2. Drug

    Phosphonothreonine

    go.drugbank.com/drugs/DB02482
    Experimental

    The phosphoric acid ester of threonine. Used as an identifier in the analysis of peptides, proteins, and enzymes. [PubChem]

  3. Drug

    D-arginine

    go.drugbank.com/drugs/DB04027
    Experimental

    A D-α-amino acid that is the D-isomer of arginine (only the L-form is physiologically active).

    Synonyms: D-2-Amino-5-guanidinovaleric acid, (R)-2-amino-5-guanidinopentanoic acid
  4. Drug

    ENMD-1198

    go.drugbank.com/drugs/DB05959
    Experimental

  5. Drug

    Mesoheme

    go.drugbank.com/drugs/DB02577
    Experimental

    The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More Rings
  6. Drug

    YSIL6

    go.drugbank.com/drugs/DB05017
    Experimental

    The molecule works by inhibiting TNF-alpha and IL-6 production in T-cells and macrophages, and by inhibiting T-cell proliferation and migration. … YSIL6 is a small-molecule drug in development for the treatment of inflammatory diseases, including rheumatoid arthritis and psoriasis.

  7. Drug

    Cilobradine

    go.drugbank.com/drugs/DB20039
    Investigational

    Cilobradine is a small molecule drug. The usage of the INN stem '-bradine' in the name indicates that Cilobradine is a bradycardic agent. … Cilobradine is under investigation in clinical trial NCT02264041 (Effect of Cytochrome P 450 3A4 Inhibition by Itraconazole on the Single Oral Dose Pharmacokinetics of Cilobradine).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  8. Drug

    Tunodafil

    go.drugbank.com/drugs/DB21576
    Investigational

    Tunodafil is a small molecule drug. The usage of the INN stem '-afil' in the name indicates that Tunodafil is a inhibitor of phosphodiesterase PDE5 with vasodilator action. … Tunodafil is under investigation in clinical trial NCT05976503 (A Study of the Interaction of Tunodafil Hydrochloride Tablets and Alcohol). Tunodafil has a monoisotopic molecular weight of 487.23 Da.

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Ulimorelin

    go.drugbank.com/drugs/DB12128
    Investigational

    of the GI tract is severely impaired. … Ulimorelin is a novel small molecule ghrelin agonist being developed by Tranzyme Pharma as a first-in-class treatment for both POI and diabetic gastroparesis, serious medical conditions in which motility

  10. Drug

    NXN-188

    go.drugbank.com/drugs/DB06096
    Investigational

    NXN-188 is a first-in-class, dual-action small molecule incorporating both neuronal nitric oxide synthase (nNOS) inhibition and 5-HT agonism that is being developed for the treatment of acute migraine.