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Displaying results 7451 - 7460 of 9715 in total
  1. Drug

    Choline alfoscerate

    go.drugbank.com/drugs/DB04660
    Investigational

    A component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids.

    Synonyms: L-alpha-Glycerophosphocholine, L-alpha-Glycerophosphorylcholine
  2. Drug

    Camptothecin

    go.drugbank.com/drugs/DB04690
    Investigational

    Camptothecin is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demon...

  3. Drug

    gamma-Butyrolactone

    go.drugbank.com/drugs/DB04699
    ExperimentalIllicit

    It is also used as a pharmacological agent and solvent. … One of the furans with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate.

    Categories: Compounds used in a research, industrial, or household setting
  4. Drug

    Lawsone

    go.drugbank.com/drugs/DB04744
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Suramin

    go.drugbank.com/drugs/DB04786
    Investigational

    A polyanionic compound with an unknown mechanism of action.

  6. Drug

    Oritavancin

    go.drugbank.com/drugs/DB04911
    ApprovedInvestigational

    [A39384,A193482,L8492] On March 12, 2021 the FDA approved Kimyrsa, a complete course of therapy in a single, 1 hour 1200 mg infusion. … [L32634] Orbactiv, the other FDA approved oritavancin product, is administered over a 3 hour infusion and contains a lower dose of 400 mg.

  7. Drug

    Lucanthone

    go.drugbank.com/drugs/DB04967
    Investigational

    It is currently being tested as a radiation sensitizer.

  8. Drug

    Canfosfamide

    go.drugbank.com/drugs/DB04972
    Investigational

    Canfosfamide is an active agent in chemotherapy-resistant ovarian cancer.

  9. Drug

    Belinostat

    go.drugbank.com/drugs/DB05015
    ApprovedInvestigational

    Belinostat is a novel agent that inhibits the enzyme histone deacetylase (HDAC) with a sulfonamide-hydroxamide structure. … It was US-approved in July 2014 as a therapeutic agent for relapsed or refractory peripheral T-cell lymphoma.

    Categories: UGT1A1 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic Index
  10. Drug

    Mitoquinone

    go.drugbank.com/drugs/DB05063
    Investigational

    -- where they accumulate up to a thousand fold. … In 2004, a genomic study of hereditary early-onset Parkinson's disease demonstrated a direct molecular link between mitochondrial dysfunction and the pathogenesis of Parkinson's disease.