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Displaying results 7461 - 7470 of 10000 in total
  1. Drug

    Acetic acid C-11

    go.drugbank.com/drugs/DB15111
    Investigational

    Using Imaging Studies PET Scan and Cardiac MRI.). … Acetic acid C-11 is under investigation in clinical trial NCT01953965 (Look at Way the Heart Functions in People With Pulmonary Hypertension (PH) Who Have Near Normal Right Ventricle (RV) Function and

  2. Drug

    Fluorofuranylnorprogesterone F-18

    go.drugbank.com/drugs/DB15282
    Investigational

    Fluorofuranylnorprogesterone F-18 is under investigation in clinical trial NCT02455453 (Assessment of Functional Status of Estrogen Receptors in Breast Cancer by Positron Emission Tomography).

  3. Drug

    Lexaptepid pegol

    go.drugbank.com/drugs/DB12578
    Investigational

    Lexaptepid pegol has been used in trials studying the treatment of Anemia, Inflammation, Chronic Diseases, End Stage Renal Disease, and Anemia of Chronic Disease.

    Categories: Nucleic Acids, Nucleotides, and Nucleosides
  4. Drug

    Terizidone

    go.drugbank.com/drugs/DB12954
    ApprovedInvestigationalWithdrawn

    Terizidone has been used in trials studying the treatment of Tuberculosis, HIV Infections, Multidrug Resistant Tuberculosis, and Extensively-drug Resistant Tuberculosis.

  5. Drug

    MDX-1379

    go.drugbank.com/drugs/DB05329
    Investigational

    This drug is underinvestigation to treat malignant melanoma.

  6. Target

    Calpain-1 catalytic subunit

    go.drugbank.com/bio_entities/BE0003346
    TargetHumans

    Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction (PubMed:19617626, PubMed:21531719, PubMed:2400579 … Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His-409' (PubMed:23707407). Cleaves and activates caspase-7 (CASP7) (PubMed:19617626)

    Synonyms: CANP 1
  7. Target

    Protein phosphatase 3 catalytic subunit alpha

    go.drugbank.com/bio_entities/BE0004238
    TargetHumans

    In response to increased Ca(2+) levels, dephosphorylates and activates phosphatase SSH1 which results in cofilin dephosphorylation (PubMed:15671020). … In response to increased Ca(2+) levels, regulates NFAT-mediated transcription probably by dephosphorylating NFAT and promoting its nuclear translocation (PubMed:26248042).

    Synonyms: CAM-PRP catalytic subunit
  8. Drug

    Resiquimod

    go.drugbank.com/drugs/DB06530
    Investigational

    It is also being studied to find out if adding it to a tumor vaccine improves the antitumor immune response. It is a type of imidazoquinoline and a type of immunomodulator. … A substance being studied in the treatment of some types of skin cancer. When put on the skin, resiquimod causes some immune cells to make certain chemicals that may help them kill tumor cells.

  9. Drug

    Foscarbidopa

    go.drugbank.com/drugs/DB16171
    Approved

    Foscarbidopa is under investigation in clinical trial NCT04379050 (Extension Study to Evaluate Safety and Tolerability of 24-hour Daily Exposure of Continuous Subcutaneous Infusion of ABBV-951 in Adult

  10. Drug

    Umbilical Cord Blood Hematopoietic Stem Cells

    go.drugbank.com/drugs/DB15723
    Investigational

    From the UCB, mononuclear cells are isolated and cultured in medium, expanded, and differentiated into the desired cell type. … The content of these cells depends and changes based on the gestational age.