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GS-441524
go.drugbank.com/drugs/DB15686InvestigationalGS-441524 is an adenosine nucleotide analog antiviral, similar to [remdesivir].[A203057,L13239] This molecule was patented in 2009.
Vilanterol
go.drugbank.com/drugs/DB09082ApprovedInvestigational[A7737] This is in response to the need for longer-acting β2-adrenergic agonists to overcome poor patient compliance (due to the frequency of dosing regimens or complexities of drug administration).
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesTaurochenodeoxycholic acid
go.drugbank.com/drugs/DB08833ExperimentalTaurochenodeoxycholic acid is an experimental drug that is normally produced in the liver. Its physiologic function is to emulsify lipids such as cholesterol in the bile.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTyramine
go.drugbank.com/drugs/DB08841InvestigationalNutraceuticalAn important characteristic of this product is its impediment to cross the blood-brain barrier which restrains its side effects to only nonpsychoactive peripheral sympathomimetic effects.
Paquinimod
go.drugbank.com/drugs/DB13118InvestigationalPaquinimod is developed for the treatment of SLE (Systemic Lupus Erythematosus), which is an autoimmune disease.
Triazavirin
go.drugbank.com/drugs/DB15622Investigational[L12087] Given the similarities between SARS-CoV-2 and H5N1, health officials are investigating Triazavirin as an option to combat SARS-CoV-2, the coronavirus responsible for COVID-19.[A191625]
AG0301-COVID19
go.drugbank.com/drugs/DB15856InvestigationalThe candidate is a plasmid DNA vaccine developed using an intradermal gene transfer method targeting the SARS-CoV-2 spike protein.
Emricasan
go.drugbank.com/drugs/DB05408InvestigationalEmricasan is the first caspase inhibitor tested in human which has received orphan drug status by FDA. It is developed by Pfizer and made in such a way that it protects liver cells from excessive apoptosis.
DTS-201
go.drugbank.com/drugs/DB06071ExperimentalDTS-201 is a prodrug of doxorubicin, a widely used anti-cancer drug that Diatos intends to develop for the treatment of various solid tumors. It is activated in the tumor environment. DTS-201 may be suitable for the treatment of many typ...