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Multiple Myeloma
go.drugbank.com/conditions/DBCOND0028259Drugs: Bortezomib · Chymotrypsin · Ciltacabtagene autoleucel · Cyclophosphamide · Daratumumab · Dexamethasone +16 moreSynonyms: Multiple myeloma, no ICD-O subtype, Multiple myeloma, no International Classification of Diseases for Oncology subtypeEsomeprazole
go.drugbank.com/drugs/DB00736ApprovedInvestigationalEsomeprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid production by covalently binding to sulfhydryl groups of cysteines found on the (H+, K+)-ATPase enzyme … [A177577, A177580] Due to their good safety profile and as several PPIs are available over the counter without a prescription, their current use in North America is widespread.
Mixtures: RUMONAL® PRO 15, RUMONAL® PRO 7.5Categories: Antiinflammatory and Antirheumatic Products, Non-Steroids, Cytochrome P-450 SubstratesTiotropium
go.drugbank.com/drugs/DB01409ApprovedInvestigational[A180163,L7084,L7087,L7090,L7093] Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation. … Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma.
Mixtures: SPIOLTO®RESPIMAT®, SPIOLTO®RESPIMAT®Categories: Agents to Treat Airway Disease, Cytochrome P-450 SubstratesAzathioprine
go.drugbank.com/drugs/DB00993ApprovedInvestigationalAzathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic … [A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of renal transplant rejection.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesSynonyms: 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine, 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurineEucalyptus oil
go.drugbank.com/drugs/DB11114ApprovedEucalyptus oil can be applied directly to the skin for pain and swelling of respiratory tract mucous membranes, joint pain, genital herpes, and nasal stuffiness. … It is shown to be effective in reducing pain, swelling, and inflammation via its modulatory effect on the immune response.
Mixtures: Zam-Buk Ointment, NORAVER UBromhexine
go.drugbank.com/drugs/DB09019ApprovedInvestigationalIt was introduced into the market in 1963, and is widely available as an over-the-counter drug in many countries. … [A233240] Recently, bromhexine and its metabolite [ambroxol] have garnered interest for the potential prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs.
Mixtures: GLICERTOX N F, TO-FLEM (GUAYACOLATO+BROMHEXINA)Synonyms: N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine, 3,5-dibromo-N(alpha)-cyclohexyl-N(alpha)-methyltoluene-alpha-2-diamineMetoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalIt is available in the oral tablet form or in solution, and can also be administered through the intravenous route.[T683] Metoclopramide was initially approved by the FDA in 1980.[A184922] … It can also be used to prevent nausea or vomiting associated with chemotherapy or certain surgical or diagnostic procedures.
Mixtures: CLIFAR® GOTAS, PLASIL®ENZIMATICOCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, P-glycoprotein substratesCTX110
go.drugbank.com/drugs/DB18626InvestigationalCTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen.
Synonyms: allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD19 antigenHypophosphatemic Rickets
go.drugbank.com/conditions/DBCOND0037223Drugs: AlfacalcidolSynonyms: HPDR I - Hypophosphatemic vitamin D-resistant rickets, HPDR I - Hypophosphataemic vitamin D-resistant ricketsNeurofibromatosis Type 1
go.drugbank.com/conditions/DBCOND0029664Synonyms: Neurofibromatosis I, Neurofibromatosis Type I