Search
Eperisone
go.drugbank.com/drugs/DB08992InvestigationalEperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (2RS)-1-(4-ethylphenyl)-2-methyl-3-(1-piperidyl)propan-1-oneCloperastine
go.drugbank.com/drugs/DB09002InvestigationalCloperastine is a cough suppressant that acts on the central nervous system.
Categories: Heterocyclic Compounds, 1-RingProducts: CLOPERAX®, LEVRONC® SUSPENSIONCefaloridine
go.drugbank.com/drugs/DB09008ApprovedWithdrawnCephaloridine or cefaloridine is a first generation semisynthetic cephalosporin. It is derived from cephalosporin C and is a zwitterion at physiological pH.
Categories: Heterocyclic Compounds, 2-RingSynonyms: ((6R,7R)-1-((2-CARBOXY-8-OXO-7-(2-(2-THIENYL)ACETAMIDO)-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-EN-3-YL)METHYL)PYRIDINIUM HYDROXIDE, INNER SALT, (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)- 7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1- azabicyclo[4.2.0]oct-2-ene-2-carboxylateArticaine
go.drugbank.com/drugs/DB09009ApprovedInvestigationalArticaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.
Mixtures: Ultracaine D-S Injection, ARTHEEK(R) ARTICAINA AL 4% CON EPINEFRINA 1:100.000Categories: Heterocyclic Compounds, 1-RingCanrenoic acid
go.drugbank.com/drugs/DB09015ApprovedInvestigationalWithdrawnLike spironolactone, it is a prodrug, which is metabolized to canrenone in the body.
Bisacodyl
go.drugbank.com/drugs/DB09020ApprovedInvestigationalBisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation. … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).
Mixtures: BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET, Dyrax-Q TabSynonyms: Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester)Efinaconazole
go.drugbank.com/drugs/DB09040ApprovedInvestigationalEfinaconazole is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the nail, known as onychomycosis.
Categories: Heterocyclic Compounds, 1-RingSynonyms: (2R,3R)-2-(2,4-Difluorophenyl)-3-(4-methylene-1-piperidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanolAtosiban
go.drugbank.com/drugs/DB09059ApprovedInvestigationalAlthough initial studies suggested it could be used as a nasal spray and hence would not require hospital admission, it is not used in that form.
Products: EVERPREM® SOLUCIÓN PARA INFUSIÓN 6.75 MG/0.9 ML, TRACTOCILE 37.5 MG/ 5 ML CONCENTRADO PARA SOLUCION POR INFUSIONVortioxetine
go.drugbank.com/drugs/DB09068ApprovedInvestigationalreceptor, an agonist of 5-HT1A, and an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors. … More specifically, vortioxetine acts via the following biological mechanisms: as a serotonin reuptake inhibitor (SRI) through inhibition of the serotonin transporter, as a partial agonist of the 5-HT1B
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: KELAC 5 MG, KELAC® 10MGTrimetazidine
go.drugbank.com/drugs/DB09069ApprovedInvestigational[A233215] It is hypothesized that trimetazidine inhibits 3-ketoacyl coenzyme A thiolase, which decreases fatty acid oxidation but not glucose metabolism, preventing the acidic conditions that exacerbate … [L33015] Trimetazidine has been studied as a treatment for angina pectoris since the late 1960s.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-[2,3,4-trimethoxybenzyl] piperazine dihydrochloride