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Displaying results 7531 - 7540 of 10000 in total
  1. Drug

    Octaverine

    go.drugbank.com/drugs/DB21449
    Experimental

    Octaverine is a small molecule drug. The usage of the INN stem '-verine' in the name indicates that Octaverine is a spasmolytic with a papaverine-like action. … Octaverine has a monoisotopic molecular weight of 397.19 Da.

  2. Drug

    Icanbelimod

    go.drugbank.com/drugs/DB21572
    Experimental

    Icanbelimod is a small molecule drug. The usage of the INN stem '-imod' in the name indicates that Icanbelimod is a immunomodulator, both stimulant/suppressive and stimulant. … Icanbelimod has a monoisotopic molecular weight of 409.18 Da.

  3. Drug

    Uplarafenib

    go.drugbank.com/drugs/DB21661
    Experimental

    Uplarafenib is a small molecule drug. The usage of the INN stem '-rafenib' in the name indicates that Uplarafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor. … Uplarafenib has a monoisotopic molecular weight of 494.12 Da.

  4. Drug

    Fosrolapitant

    go.drugbank.com/drugs/DB21723
    Investigational

    Fosrolapitant is a small molecule drug. The usage of the INN stem '-pitant' in the name indicates that Fosrolapitant is a neurokinin NK1​ (substance P) receptor antagonist. … Fosrolapitant has a monoisotopic molecular weight of 654.16 Da.

  5. Drug

    Flezurafenib

    go.drugbank.com/drugs/DB21725
    Experimental

    Flezurafenib is a small molecule drug. The usage of the INN stem '-rafenib' in the name indicates that Flezurafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor. … Flezurafenib has a monoisotopic molecular weight of 456.16 Da.

  6. Drug

    Relutrigine

    go.drugbank.com/drugs/DB21614
    Investigational

    Relutrigine is a small molecule drug. The usage of the INN stem '-trigine' in the name indicates that Relutrigine is a sodium channel blocker, signal transduction modulator. … Relutrigine is under investigation in clinical trial NCT07010471 (A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine).

  7. Drug

    Rebastinib

    go.drugbank.com/drugs/DB13005
    Investigational

    Rebastinib has been used in trials studying the treatment of Chronic Myeloid Leukemia. It is an inhibitor of Tie2 tyrosine kinase receptor and an antineoplastic agent.

  8. Drug

    Idetrexed

    go.drugbank.com/drugs/DB21469
    Investigational

    Idetrexed is a small molecule drug. The usage of the INN stem '-trexed' in the name indicates that Idetrexed is a antineoplastic; thymidilate synthetase inhibitor. … Idetrexed is under investigation in clinical trial NCT02360345 (Phase I Trial of ONX-0801 Once Weekly or Alternate Weekly). Idetrexed has a monoisotopic molecular weight of 647.22 Da.

  9. Drug

    Telcagepant

    go.drugbank.com/drugs/DB12228
    Investigational

    It is an antagonist of the receptor for calcitonin gene-related peptide (CGRP), a primary neuropeptide involved in the pathophysiology of migraine. … CGRP and its receptors are found in areas of the central and peripheral nervous system that are important for the transmission of migraine pain.

  10. Drug

    Promestriene

    go.drugbank.com/drugs/DB12487
    Investigational

    Promestriene (3-propyl ethyl, 17B-methyl estradiol) has been used in trials studying the prevention of Hypospadias. It is a synthetic estrogen analog, which is used in topical estrogen therapy. … It has been also studied in phase III of the clinical trial in the post-operative patients with hypospadias.