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Displaying results 7541 - 7550 of 10000 in total
  1. Drug

    Eritoran

    go.drugbank.com/drugs/DB04933
    Investigational

    Eritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). It is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.

    Categories: Toll-Like Receptor 4, antagonists & inhibitors
  2. Drug

    Creatinolfosfate

    go.drugbank.com/drugs/DB13071
    Investigational

    COP is under investigation for the treatment of Rheumatoid Arthritis, Mature B-Cell Lymphoma, and Noninflammatory Degenerative Joint Disease. … COP has been investigated for the treatment of Diabetic Retinopathy.

  3. Drug

    AMP-201

    go.drugbank.com/drugs/DB18663
    Experimental

    AMP-201 comprises an adeno-associated virus type 8 vector (AAV8) encoding the collagen Q gene (COLQ). It is under investigation for the treatment of collagen Q congenital myasthenia.

    Synonyms: Adeno Associated Virus Serotype 8 Encoding the Collagen Q Gene
  4. Drug

    Cedirogant

    go.drugbank.com/drugs/DB18951
    Investigational

    Cedirogant is under investigation in clinical trial NCT05044234 (A Study to Assess Adverse Events and Disease Activity With Cedirogant (ABBV-157) in Adult Participants With Moderate to Severe Psoriasis

    Synonyms: (1-(2,4-dichloro-3-((7-chloro-5-(trifluoromethyl)-1hindol-1-yl)methyl)benzoyl)piperidin-4-yl)acetic acid, 4-piperidineacetic acid, 1-(2,4-dichloro-3-((7-chloro-5-(trifluoromethyl)-1h-indol-1-yl)methyl)benzoyl)-
  5. Drug

    Upacicalcet

    go.drugbank.com/drugs/DB20023
    Investigational

    Upacicalcet is a small molecule drug. The usage of the INN stem '-calcet/-calcet-' in the name indicates that Upacicalcet is a calcium-sensing receptor (CaSR) agonist. … Upacicalcet is under investigation in clinical trial NCT05836220 (Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-2). Upacicalcet has a monoisotopic molecular weight of 351.03 Da.

  6. Drug

    Atuveciclib

    go.drugbank.com/drugs/DB20084
    Investigational

    Atuveciclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Atuveciclib is a cyclin dependant kinase inhibitor. … Atuveciclib is under investigation in clinical trial NCT02345382 (Phase I Dose Escalation of BAY1143572 in Subjects With Acute Leukemia). Atuveciclib has a monoisotopic molecular weight of 387.12 Da.

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Lapretolimod

    go.drugbank.com/drugs/DB20120
    Investigational

    Lapretolimod is a small molecule drug. The usage of the INN stem '-tolimod' in the name indicates that Lapretolimod is a toll-like receptor (TLR) agonist. … Lapretolimod is under investigation in clinical trial NCT03799510 (Anti-Schistosomiasis Vaccine: Sm14 Phase 2b-Sn in School Children). Lapretolimod has a monoisotopic molecular weight of 1745.28 Da.

    Synonyms: Glucopyranosyl lipid a
  8. Drug

    Bavtavirine

    go.drugbank.com/drugs/DB21527
    Investigational

    Bavtavirine is a small molecule drug. The usage of the INN stem '-virine' in the name indicates that Bavtavirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). … Bavtavirine is under investigation in clinical trial NCT05585307 (Study of Novel Antiretrovirals in Participants With HIV-1). Bavtavirine has a monoisotopic molecular weight of 416.17 Da.

  9. Drug

    Alofanib

    go.drugbank.com/drugs/DB20918
    Investigational

    Alofanib is a small molecule drug. The usage of the INN stem '-anib' in the name indicates that Alofanib is a angiogenesis inhibitor. … Alofanib is under investigation in clinical trial NCT04071184 (Study of Alofanib in Patients With Metastatic Gastric Cancer). Alofanib has a monoisotopic molecular weight of 413.07 Da.

  10. Drug

    Rupintrivir

    go.drugbank.com/drugs/DB05102
    Experimental

    Rupintrivir was active against all 48 HRV serotypes tested in a cell protection assay in H1-HeLa cells. It is designed to combat colds caused by rhinovirus. … Rupintrivir is a rhinovirus 3C protease inhibitor in development for use against human rhinoviral (HRV) infections.

    Categories: Heterocyclic Compounds, 1-Ring