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ATX-914
go.drugbank.com/drugs/DB12673InvestigationalAxt914 is under investigation in clinical trial NCT00417261 (Safety, Tolerability, Pharmacodynamic and Pharmacokinetic Effects of Single and Multiple-Doses of ATF936 and AXT914 Administered Orally in Healthy
Categories: Heterocyclic Compounds, 2-RingIntepirdine
go.drugbank.com/drugs/DB12680InvestigationalIntepirdine has been used in trials studying the treatment of Alzheimer's Disease.
Categories: Heterocyclic Compounds, 2-RingMubritinib
go.drugbank.com/drugs/DB12682InvestigationalMubritinib has been used in trials studying the treatment of Lung Neoplasm, Renal Neoplasm, Breast Neoplasm, Ovarian Neoplasm, and Pancreatic Neoplasm.
Categories: Heterocyclic Compounds, 1-RingPHA-793887
go.drugbank.com/drugs/DB12686InvestigationalPHA-793887 has been used in trials studying the treatment of Advanced/Metastatic Solid Tumors.
Categories: Heterocyclic Compounds, 1-RingLY-2584702
go.drugbank.com/drugs/DB12690InvestigationalLY2584702 has been used in trials studying the treatment of Cancer, Advanced Cancer, Renal Cell Carcinoma, Metastases, Neoplasm, and Neuroendocrine Tumors, among others.
Categories: Ribosomal Protein S6 Kinases, 70-kDa, antagonists & inhibitors, Heterocyclic Compounds, 1-RingIbalizumab
go.drugbank.com/drugs/DB12698ApprovedInvestigationalIbalizumab (also known as _ibalizumab-uiyk_ and formerly known as TNX-355) is a monoclonal antibody that binds to CD4 receptors on the surface of CD4-positive cells, preventing HIV particle entry into … In October 2022, the FDA approved the administration of Trogarzo (ibalizumab-uiyk) by intravenous push, allowing for a faster drug administration.[L43443,L43448]
Categories: HIV 1 Post-attachment Fusion Inhibitors, Human Immunodeficiency Virus 1 Post-attachment Fusion InhibitorSpiradoline
go.drugbank.com/drugs/DB12704InvestigationalSpiradoline has been investigated for the basic science of Bipolar Depression.
Categories: Heterocyclic Compounds, 1-RingFuzapladib
go.drugbank.com/drugs/DB19478ExperimentalFuzapladib is a small molecule drug. The usage of the INN stem '-pladib' in the name indicates that Fuzapladib is a phospholipase A2 inhibitor. … Fuzapladib has a monoisotopic molecular weight of 379.12 Da.
Categories: Heterocyclic Compounds, 1-Ring, Phospholipases A, antagonists & inhibitorsDetirelix
go.drugbank.com/drugs/DB19488ExperimentalDetirelix is a small molecule drug. The usage of the INN stem '-relix' in the name indicates that Detirelix is a gonadotropin-releasing-hormone (GnRH) inhibitor. … Detirelix has a monoisotopic molecular weight of 1536.78 Da.
Cefoselis
go.drugbank.com/drugs/DB19513ExperimentalCefoselis is a small molecule drug. Cefoselis has a monoisotopic molecular weight of 522.11 Da.
Categories: Heterocyclic Compounds, 2-Ring