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Tifcemalimab
go.drugbank.com/drugs/DB18914InvestigationalTifcemalimab is under investigation in clinical trial NCT06095583 (Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell
Cimlanod
go.drugbank.com/drugs/DB14983InvestigationalCimlanod is under investigation in clinical trial NCT02819271 (A First-in-Human Study of the Safety of Single Continuous Intravenous (IV) Infusions of CXL-1427 for up to 48 Hours in Healthy Volunteers)
Budigalimab
go.drugbank.com/drugs/DB16668InvestigationalWith IV Modified FOLFIRINOX (Mffx) With or Without IV Budigalimab Compared to Mffx in Adult Participants With Untreated Pancreatic Cancer Metastasis). … Budigalimab is under investigation in clinical trial NCT04807972 (Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 Is Administered in Combination
Siagoside
go.drugbank.com/drugs/DB12351InvestigationalTreatment results in a 52% decrease in mortality 48 hours after the induction of ischemia in gerbils by permanent unilateral ligation of the common carotid artery. … It is a naturally occurring substance in the nerve cell’s membrane that is thought to play a role in cell growth, development, and repair.
BNT162a1 SARS-CoV-2 Vaccine
go.drugbank.com/drugs/DB15697Experimental[L15002, L15007] BNT162a1 is undergoing evaluation in clinical trials in both the USA (NCT04368728) and Germany (NCT04380701).[L15017, L15022] … [L15002, L15007] BNT162a1 is a uridine mRNA (uRNA) vaccine formulated in lipid nanoparticles for delivery via intramuscular injection.
BNT162c2 SARS-CoV-2 Vaccine
go.drugbank.com/drugs/DB15698Experimental[L15002, L15007] BNT162c2 is undergoing evaluation in clinical trials in both the USA (NCT04368728) and Germany (NCT04380701).[L15017, L15022] … [L15002, L15007] BNT162c2 is a self-amplifying mRNA (saRNA) vaccine formulated in lipid nanoparticles for delivery via intramuscular injection.
CIGB 2020 Vaccine
go.drugbank.com/drugs/DB15808ExperimentalThe vaccine was developed and tested by the Center for Genetic Engineering and Biotechnology (CIGB), in Havana Cuba. … CIGB 2020 is a vaccine candidate administered nasally and sublingually, working to strengthen immunity in the areas administered.
Orludodstat
go.drugbank.com/drugs/DB21498InvestigationalOrludodstat is under investigation in clinical trial NCT03404726 (A Study to Investigate BAY2402234, a Dihydroorotate Dehydrogenase (DHODH) Inhibitor, in Myeloid Malignancies). … The usage of the INN stem '-dodstat' in the name indicates that Orludodstat is a dihydro-orotate dehydrogenase (DHODH) inhibitor.
Radequinil
go.drugbank.com/drugs/DB19722InvestigationalRadequinil is under investigation in clinical trial NCT00359944 (Safety and Efficacy Study of AC-3933 in Adults With Mild to Moderate Alzheimer's Disease). … The usage of the INN stem '-nil' in the name indicates that Radequinil is a benzodiazepine receptor antagonist/agonist.
Revexepride
go.drugbank.com/drugs/DB20324InvestigationalRevexepride is under investigation in clinical trial NCT01472939 (Selective 5-HT4 Receptor Agonist and Proton Pump Inhibitor (PPI) in Subjects With Gastroesophageal Reflux Disease (GERD)). … The usage of the INN stem '-pride' in the name indicates that Revexepride is a sulpiride derivative and analogue.