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Nolatrexed
go.drugbank.com/drugs/DB12912ExperimentalNolatrexed is under investigation in clinical trial NCT00012324 (Nolatrexed Dihydrochloride Compared With Doxorubicin in Treating Patients With Recurrent or Unresectable Liver Cancer).
Lurtotecan
go.drugbank.com/drugs/DB12222InvestigationalLurtotecan is under investigation in clinical trial NCT00022594 (Liposomal Lurtotecan in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer).
ARX517
go.drugbank.com/drugs/DB23076InvestigationalARX517 is under investigation in clinical trial NCT04662580 (ARX517/JNJ-95298177 as Monotherapy or Combination Therapy in Subjects With Metastatic Prostate Cancer).
(R)-acetoin
go.drugbank.com/drugs/DB04364ExperimentalIt is a component of the butanediol cycle in microorganisms. In mammals it is oxidized to carbon dioxide.
(S)-acetoin
go.drugbank.com/drugs/DB02788ExperimentalIt is a component of the butanediol cycle in microorganisms. In mammals it is oxidized to carbon dioxide.
Obefazimod
go.drugbank.com/drugs/DB14828InvestigationalABX-464 is under investigation in clinical trial NCT03905109 (Safety Evaluation of ABX464 in Patients With Moderate to Severe Active Crohn's Disease).
Elsubrutinib
go.drugbank.com/drugs/DB18850InvestigationalElsubrutinib is under investigation in clinical trial NCT04451772 (A Study of the Safety of Oral Elsubrutinib Capsules and Oral Upadacitinib Tablets Given Alone or in Combination (ABBV-599) for Adult Participants … With Moderately to Severely Active Systemic Lupus Erythematosus to Assess Change in Disease State).
Velusetrag
go.drugbank.com/drugs/DB12702InvestigationalVelusetrag has been used in trials studying the treatment of Gastroparesis and Alzheimer's Disease. … It is a highly selective serotonin receptor agonist effective in patients with chronic constipation. It is being developed by Theravance.
Icenticaftor
go.drugbank.com/drugs/DB21466InvestigationalIcenticaftor is under investigation in clinical trial NCT04396366 (Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of QBW251 in Subjects With Bronchiectasis). … The usage of the INN stem '-caftor' in the name indicates that Icenticaftor is a Cystic fibrosis transmembrane regulator (CFTR) protein modulator, corrector, and amplifier.
Linvencorvir
go.drugbank.com/drugs/DB21544InvestigationalLinvencorvir is under investigation in clinical trial NCT04225715 (A Trial To Evaluate The Efficacy And Safety Of Multiple Combination Therapies In Participants With Chronic Hepatitis B). … The usage of the INN stem '-corvir' in the name indicates that Linvencorvir is a core protein (Cp) inhibitor.