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Bemegride
go.drugbank.com/drugs/DB13740ExperimentalBemegride is a CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose.
Apricitabine
go.drugbank.com/drugs/DB12855InvestigationalApricitabine has been used in trials studying the treatment of HIV Infections.
177Lu-PSMA-I&T
go.drugbank.com/drugs/DB22176Investigational177Lu-PSMA-I&T is under investigation in clinical trial NCT04886986 (Phase I/II 225Ac-J591 Plus 177Lu-PSMA-I&T for Progressive Metastatic Castration Resistant Prostate Cancer).
Synonyms: 177Lu-PSMA I&T, 177Lu-PSMA-I&TOPB-111077
go.drugbank.com/drugs/DB16630InvestigationalOPB-111077 is a novel inhibitor of STAT3 and mitochondrial oxidative phosphorylation. It has demonstrated promising anticancer activity in preclinical models.
HMI-103
go.drugbank.com/drugs/DB17684InvestigationalHMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene, mutated in people with phenylketonuria.
RCT1100
go.drugbank.com/drugs/DB18830InvestigationalRCT1100 is an investigational mRNA-based therapeutic that aims to treat primary ciliary dyskinesia caused by pathogenic mutations in DNAI1.[L50788]
EA-230
go.drugbank.com/drugs/DB19114InvestigationalEA-230 is under investigation in clinical trial NCT03145220 (Immunomodulation of EA-230 Following On-pump Coronary Artery Bypass Grafting (CABG)).
Tiazofurine
go.drugbank.com/drugs/DB13243ExperimentalTiazofurine has potential clinical use in cancer treatment as it is a potential inhibitor of Inosine- 5’-monophosphate (IMP) dehydrogenase [A174991].
Dihydroxyacetone
go.drugbank.com/drugs/DB01775ExperimentalIt is readily phosphorylated to dihydroxyacetone phosphate by triokinase in erythrocytes. In combination with naphthoquinones it acts as a sunscreening agent. [PubChem] … Its addition to blood preservation solutions results in better maintenance of 2,3-diphosphoglycerate levels during storage.