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Idasanutlin
go.drugbank.com/drugs/DB12325InvestigationalIdasanutlin has been used in trials studying the treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and Neoplasms, Leukemia, Acute Myeloid Leukemia.
Synonyms: BENZOIC ACID, 4-((((2R,3S,4R,5S)-3-(3-CHLORO-2-FLUOROPHENYL)-4-(4-CHLORO-2-FLUOROPHENYL)-4-CYANO-5-(2,2-DIMETHYLPROPYL)-2-PYRROLIDINYL)CARBONYL)AMINO)-3-METHOXY-Categories: Heterocyclic Compounds, 1-Ring, Proto-Oncogene Proteins c-mdm2, antagonists & inhibitorsSalvinorin A
go.drugbank.com/drugs/DB12327InvestigationalSalvinorin A has been investigated for the basic science of Pharmaceutical Preparations.
Synonyms: Salvinorin AAmcipatricin
go.drugbank.com/drugs/DB12333InvestigationalSPK-843 doses of higher than 1.0 mg/kg of body weight exhibit no renal toxicities and a tendency toward better survival prolongation than the estimated maximum tolerated doses of amphotericin B (Fungizone … In preclinical models, SPK-843 shows in vitro inhibitory activity comparable to or better than that of Amphotericin B against Candida spp., Cryptococcus neoformans, and Aspergillus spp.
Nilofabicin
go.drugbank.com/drugs/DB12347InvestigationalCG400549 has been used in trials studying the treatment of Skin Infection.
Categories: Heterocyclic Compounds, 1-Ring5-amino-1,3,4-thiadiazole-2-thiol
go.drugbank.com/drugs/DB12348InvestigationalATT has been investigated in Pulmonary Tuberculosis.
Categories: Heterocyclic Compounds, 1-RingPiclozotan
go.drugbank.com/drugs/DB12361InvestigationalPiclozotan has been investigated for the treatment of Parkinson's Disease.
Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT1 Receptor AgonistsVestronidase alfa
go.drugbank.com/drugs/DB12366ApprovedInvestigationalVestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. … The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as human beta-glucuronidase (GUS) [FDA Label].
AZD-3839
go.drugbank.com/drugs/DB12368InvestigationalAZD3839 has been used in trials studying the basic science of Safety, Tolerability, Alzheimer's Disease, and Blood Concentration.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingApricoxib
go.drugbank.com/drugs/DB12378InvestigationalApricoxib has been used in trials studying the treatment and prevention of Lung Cancer, Breast Cancer, Pancreatic Cancer, Non Small Cell Lung Cancer, and Metastatic Pancreatic Cancer, among others.
Categories: Heterocyclic Compounds, 1-RingMerestinib
go.drugbank.com/drugs/DB12381InvestigationalMerestinib has been used in trials studying the treatment of Cancer, Solid Tumor, Advanced cancer, ColoRectal Cancer, and Metastatic Cancer, among others.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring