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Displaying results 7681 - 7690 of 10000 in total
  1. Drug

    APT3111

    go.drugbank.com/drugs/DB06390
    Experimental

    APT3111 is an investigational drug used to treat PNH (paroxysmal nocturnal haemoglobinurea).

  2. Drug

    AC3056

    go.drugbank.com/drugs/DB05230
    Experimental

    AC3056 is a non-peptide antioxidant that acts as an inhibitor of vascular cell adhesion molecule expression originally developed by Aventis Pharmaceuticals. … It as since been acquired by Amylin Pharmaceuticals and has completed phase I trials.

  3. Drug

    AEG35156

    go.drugbank.com/drugs/DB06184
    Investigational

    AEG35156 selectively blocks the cellular expression of X-linked inhibitor of apoptosis protein (XIAP), a pivotal inhibitor of apoptosis that is overexpressed in many tumors. … This agent reduces total levels of XIAP in tumor cells, working synergistically with cytotoxic drugs to overcome tumor cell resistance to apoptosis.

  4. Drug

    DPDPE

    go.drugbank.com/drugs/DB08861
    Experimental

    A heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  5. Drug

    DTx-1252

    go.drugbank.com/drugs/DB18086
    Experimental

    DTx-1252 is a siRNA therapeutic under investigation for the treatment of Charcot-Marie-Tooth Disease type 1A (CMTD1A).[L48096]

  6. Drug

    Ulixertinib

    go.drugbank.com/drugs/DB13930
    Investigational

    It is currently in clinical trials for the treatment of a wide range of tumors. … Ulixertinib is a a novel, reversible, ATP-competitive ERK1/2 inhibitor with high potency and ERK1/2 selectivity [A31474].

  7. Drug

    VTP-27999

    go.drugbank.com/drugs/DB12416
    Investigational

    VTP-27999 has been used in trials studying the basic science of Renal Function.

    Categories: Agents Acting on the Renin-Angiotensin System
  8. Drug

    Dectrekumab

    go.drugbank.com/drugs/DB14789
    Investigational

    Dectrekumab is under investigation in clinical trial NCT00987545 (Efficacy 2 Part Study of Identification of Keloid Biomarkers and Effect of QAX576 on Keloid Recurrence).

  9. Drug

    Safimaltib

    go.drugbank.com/drugs/DB21528
    Investigational

    Safimaltib is a small molecule drug. Safimaltib is under investigation in clinical trial NCT06788509 (A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring).

  10. Drug

    Morinamide

    go.drugbank.com/drugs/DB13417
    Investigational

    Categories: Antiinfectives for Systemic Use, Drugs for Treatment of Tuberculosis