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Pegvisomant
go.drugbank.com/drugs/DB00082ApprovedInvestigationalPegvisomant is a highly selective growth hormone (GH) receptor antagonist. It is used to treat acromegaly.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: SOMAVERT® 15 MG POLVO LIOFILIZADO PARA SOLUCIÓN INYECTABLE, SOMAVERT 15 MG ENJEKSIYONLUK COZELTI ICIN TOZ ICEREN FLAKON VE COZUCU, 30 ADETEmpagliflozin
go.drugbank.com/drugs/DB09038ApprovedInvestigational[A203453] It is used clinically as an adjunct to diet and exercise, often in combination with other drug therapies,[L13673,L13679,L11479] for the management of type 2 diabetes mellitus. … [A203501] Attempts at overcoming these limitations first saw the development of O-glucoside analogs of phlorizin (e.g.
Mixtures: JARDIANCE DUO® 5 MG / 850 MG, GLYXAMBI® 10 MG/ 5 MGSynonyms: (1S)-1,5-anhydro-1-(4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl)-D-glucitolClopidogrel
go.drugbank.com/drugs/DB00758ApprovedInvestigationalClopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. … L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI
Mixtures: ATELIT-DUO® 75/100 MG TABLETAS, KLOGEL-A 75/100 MG KAPSUL, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesPalbociclib
go.drugbank.com/drugs/DB09073ApprovedInvestigationalIt is a second generation cyclin-dependent kinase inhibitor[A176798] selected from a group of pyridopyrimidine compounds due to its favorable physical and pharmaceutical properties. … Palbociclib is a piperazine pyridopyrimidine[A176792] that acts in the cell cycle machinery.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-8h-pyrido(2,3-d)pyrimidin-7-one, 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-oneEnsulizole
go.drugbank.com/drugs/DB11115ApprovedIt is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths.
Mixtures: Marcelle/ Oil Free Multi-Défense Lotion SPF 15 Fps/ Fluide Multi-Défense Sans Huile, Creme Solaire Haute Protection Special Enfants Et Peaux Reactives Au Soleil SPF 30Products: Tattoo Color Guard SPF 15, Covergirl Queen Collection All Day Flawless 3in1 Foundation Broad Spectrum SPF 20 - Q800 SandMiglustat
go.drugbank.com/drugs/DB00419ApprovedInvestigationalMiglustat was first developed as an anti-HIV agent in the 1990s. … Miglustat, commonly marketed under the trade name Zavesca, is a drug used to treat Gaucher disease.
Synonyms: 1,5-(butylimino)-1,5-dideoxy, D-glucitolProducts: ZAVESCA® 100 MG, Miglustat G.L. 100 mg-HartkapselnJanssen COVID-19 Vaccine
go.drugbank.com/drugs/DB15857ApprovedInvestigationalA preclinical study in hamsters infected with SARS-COV-2 infection[A220053] showed a single immunization with the vaccine-elicited neutralizing responses and protected against SARS-CoV-2 induced pneumonia … SARS-COV-2 challenge.
Synonyms: Adenovirus type 26 encoding SARS-COV-2 spike glycoproteinMitomycin
go.drugbank.com/drugs/DB00305ApprovedInvestigationalTract Urothelial Cancer (LG-UTUC)[L12867] - as well as adjunctly to _ab externo_ glaucoma surgeries. … [L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix.
Categories: Compounds used in a research, industrial, or household settingProducts: MITOMYCIN-C KYOWA FOR INJECTION 10 mg/vial, Mitomycin C "Kyowa" 10 mg - TrockenstechampullenDexibuprofen
go.drugbank.com/drugs/DB09213ApprovedWithdrawnIt is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer. … Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesSynonyms: d-ibuprotenLinagliptin
go.drugbank.com/drugs/DB08882ApprovedInvestigationalLinagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes [L9557]. … Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding[A37050
Mixtures: GLYXAMBI® 10 MG/ 5 MG, GLYXAMBI® 10 MG/ 5 MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors