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Displaying results 761 - 770 of 10000 in total
  1. Drug

    Donepezil

    go.drugbank.com/drugs/DB00843
    ApprovedInvestigational

    [L7916,L7937] A donepezil transdermal delivery system, Adlarity, was approved by the FDA in March 2022 for the treatment of Alzheimer's dementia. … In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990.

    Products: DONEPEZIL EG, Pro-donepezil
  2. Drug

    Magnesium chloride

    go.drugbank.com/drugs/DB09407
    ApprovedInvestigational

    Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.

    Mixtures: D-12043 Sol Conc Electrolyt Pour Dialy, SOLUCION DP PISA 2.5%(MODIFICADA EN MAGNESIO Y LACTATO)Products: Magnesium Chloride for Hemodialysis 5.15
  3. Drug

    Iodine

    go.drugbank.com/drugs/DB05382
    ApprovedInvestigational

    Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. … Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]

    Mixtures: Ni-C-E-LE Plus, De La Cruz Tincture of IodineProducts: JCI MN Colloidal Iodine Immune-improving Water, JCI MN Colloidal Iodine Eye Wash Cleansing Water (Quasi Drug)
  4. Drug

    Hydrocortisone

    go.drugbank.com/drugs/DB00741
    ApprovedInvestigationalVet approved

    Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex.[A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. … [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone.

    Synonyms: (11β)-11,17,21-trihydroxypregn-4-ene-3,20-dioneInternational brands: Ala-Scalp
  5. Target

    Pol polyprotein

    go.drugbank.com/bio_entities/BE0003079
    TargetEIAV

    During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.

    Polypeptides: Pol polyprotein
  6. Drug

    Rosuvastatin

    go.drugbank.com/drugs/DB01098
    ApprovedInvestigational

    events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks. … as well as the need for surgical revascularization or angioplasty following a heart attack.

    Mixtures: ROSUVINA LEGRAND® E 10/40, ROSUVINA LEGRAND® E 10/20Categories: Drugs Used in Diabetes, Hypolipidemic Agents Indicated for Hyperlipidemia
  7. Drug

    Sunitinib

    go.drugbank.com/drugs/DB01268
    ApprovedInvestigational

    For these purposes, sunitinib is generally available as an orally administered formulation. Sunitinib inhibits cellular signaling by targeting multiple RTKs. … Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor.

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic IndexProducts: SUNITINIB EG, Sunitinib 1A Pharma 12,5 mg - Hartkapseln
  8. Drug

    Clotrimazole

    go.drugbank.com/drugs/DB00257
    ApprovedInvestigationalVet approved

    This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s [A174094]. … As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and some cancers [A174094].

    Mixtures: TOR CREMA DERMATOLOGICA, SAEROGENTA-A CREAMCategories: Antifungals for Topical Use, Antifungals for Dermatological Use
  9. Target

    Gag-Pol polyprotein

    go.drugbank.com/bio_entities/BE0001265
    Target

    Gag-Pol polyprotein may regulate its own translation, by the binding genomic RNA in the 5'-UTR. … Gag-Pol polyprotein Mediates, with Gag polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical

    Polypeptides: Gag-Pol polyproteinSynonyms: Pr160Gag-Pol
  10. Target

    Gag-Pol polyprotein

    go.drugbank.com/bio_entities/BE0001342
    Target

    Gag-Pol polyprotein may regulate its own translation, by the binding genomic RNA in the 5'-UTR. … Gag-Pol polyprotein Mediates, with Gag polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical

    Polypeptides: Gag-Pol polyproteinSynonyms: Pr160Gag-Pol