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Baculoviral IAP repeat-containing protein 1
go.drugbank.com/bio_entities/BE0010810TargetHumansAnti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasi...
Polypeptides: Baculoviral IAP repeat-containing protein 1Tyrosine-protein kinase transmembrane receptor ROR2
go.drugbank.com/bio_entities/BE0010827TargetHumansMay act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443) … Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity).
Polypeptides: Tyrosine-protein kinase transmembrane receptor ROR2Synonyms: Neurotrophic tyrosine kinase, receptor-related 2Killer cell immunoglobulin-like receptor 2DL2
go.drugbank.com/bio_entities/BE0010848TargetHumansReceptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis
Polypeptides: Killer cell immunoglobulin-like receptor 2DL2Synonyms: p58 NK receptor CL-43, p58 natural killer cell receptor clone CL-43Killer cell immunoglobulin-like receptor 3DL2
go.drugbank.com/bio_entities/BE0010849TargetHumansReceptor on natural killer (NK) cells and T cells for MHC class I molecules (PubMed:24018270, PubMed:28636952). … Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity (PubMed:26928464)
Polypeptides: Killer cell immunoglobulin-like receptor 3DL2Synonyms: p70 NK receptor CL-5, p70 natural killer cell receptor clone CL-5Interleukin-22 receptor subunit alpha-1
go.drugbank.com/bio_entities/BE0016650TargetHumansComponent of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. … Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation.
Polypeptides: Interleukin-22 receptor subunit alpha-1Synonyms: IL-22 receptor subunit alpha-1, Cytokine receptor class-II member 9Taste receptor type 2 member 3
go.drugbank.com/bio_entities/BE0023234TargetHumansGustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5
Polypeptides: Taste receptor type 2 member 3Function: bitter taste receptor activityT cell receptor beta variable 13
go.drugbank.com/bio_entities/BE0023663TargetHumansV region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).
Polypeptides: T cell receptor beta variable 13T cell receptor delta variable 2
go.drugbank.com/bio_entities/BE0023749TargetHumansV region of the variable domain of T cell receptor (TR) delta chain that participates in the antigen recognition (PubMed:24600447).
Polypeptides: T cell receptor delta variable 2Arbutin
go.drugbank.com/drugs/DB11217ApprovedExtracted from the dried leaves of bearberry plant in the genus Arctostaphylos and other plants commonly in the Ericaceae family, arbutin is a beta-D-glucopyranoside of DB09526. It is found in foods, over-the-counter drugs, and herbal di...
Mixtures: Wonder Intensive BBCream 21 (Light)Aloe vera leaf
go.drugbank.com/drugs/DB13906ApprovedInvestigationalAloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands. Aloe vera, or Aloe barbadensis miller, is the most common species of Aloe that is cultivated for agr...