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SAR421869
go.drugbank.com/drugs/DB17909InvestigationalSAR421869 is a Lentiviral Vector Containing The Human My07A Gene currently being investigated for the treatment of retinitis pigmentosa associated with Usher syndrome 1B gene defect.
AZD2315
go.drugbank.com/drugs/DB06540ExperimentalThe drug AZD2315, an immunosuppressant developed by AstraZeneca, was in Phase 1 clinical trials for the treatment of rheumatoid arthritis but was discontinued during this phase
Porphobilinogen
go.drugbank.com/drugs/DB02272ExperimentalIt is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme porphobilinogen deaminase.
BT200
go.drugbank.com/drugs/DB18333Investigational[A261491] It is under investigation for the treatment of von Willebrand disease and hemophilia A.[L48156] … BT200 (Rondoraptivon pegol) is a PEGylated anti-von Willebrand factor (VWF) aptamer targeted against the VWF A1 domain.
BGT-DTDS
go.drugbank.com/drugs/DB18664ExperimentalIt is under investigation for the treatment of dopamine transporter deficiency syndrome (DTDS). … BGT-DTDS is an investigational gene therapy comprising an adeno-associated viral vector type 2 (AAV2) encoding the human _SLC6A3_ gene.
Synonyms: Adeno-associated viral vector serotype 2 containing the human SLC6A3 geneCry5B
go.drugbank.com/drugs/DB17783ExperimentalCry5B is a pore-forming crystal protein produced by and derived from the soil bacterium _Bacillus thuringiensis_. … With demonstrated anthelmintic properties, it has been investigated in the treatment of parasitic intestinal infections.[A259372, A259377]
2X-121
go.drugbank.com/drugs/DB16063Investigational2X-121 is under investigation in clinical trial NCT03562832 (Investigation of Anti-tumour Effect and Tolerability of the PARP Inhibitor 2X-121 in Patients With Metastatic Breast Cancer Selected by the
Sonepcizumab
go.drugbank.com/drugs/DB06305InvestigationalS1P is the extracellular ligand for the G protein-coupled lysophospholipid receptor EDG-1 (endothelial differentiation gene-1). … Upon administration, sonepcizumab binds S1P, which may result in the inhibition of tumor angiogenesis.
Tasurgratinib
go.drugbank.com/drugs/DB21222InvestigationalThe usage of the INN stem '-gratinib' in the name indicates that Tasurgratinib is a fibroblast growth factor receptor (FGFR) inhibitor.
Synonyms: E 7090