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Emopamil
go.drugbank.com/drugs/DB14064ExperimentalPrevents renal injury after warm & cold ischemia.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates8-chlorotheophylline
go.drugbank.com/drugs/DB14132Experimental8-Chlorotheophylline is a stimulant drug of the xanthine chemical class, with physiological effects similar to caffeine. Its main use is in combination with Diphenhydramine as the antiemetic drug Dimenhydrinate. The stimulant properties ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSophora flavescens root
go.drugbank.com/drugs/DB14565InvestigationalSynonyms: Ku shenCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsFluprednisolone acetate
go.drugbank.com/drugs/DB14637ExperimentalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDexamethasone acetate
go.drugbank.com/drugs/DB14649ApprovedInvestigationalVet approvedCommonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions. Developed in 1957, dexamethasone is stru...
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsMelengestrol acetate
go.drugbank.com/drugs/DB14659ExperimentalA 6-methyl progesterone acetate with reported glucocorticoid activity and effect on estrus.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersTemsavir
go.drugbank.com/drugs/DB14675InvestigationalCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesPegzilarginase
go.drugbank.com/drugs/DB14780ApprovedPegzilarginase is a recombinant, cobalt-substituted, and pegylated human arginase 1 enzyme therapy designed to address the underlying metabolic deficit in arginase 1 deficiency (ARG1-D). … FDA in February 2026 for the treatment of hyperargininemia in adult and pediatric patients aged 2 years and older with ARG1-D, to be used in conjunction with dietary protein restriction.
ONO-2952
go.drugbank.com/drugs/DB14802Investigationalinvestigation in clinical trial NCT01887002 (Study to Evaluate the Effects of ONO-2952 on Pain Perception Produced by Rectal Distention in Female Subjects With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)
Myrcludex B
go.drugbank.com/drugs/DB14853InvestigationalClinical Study to Assess Efficacy and Safety of 3 Doses of Myrcludex B for 24 Weeks in Combination With Tenofovir Compared to Tenofovir Alone to Suppress HBV Replication in Patients With Chronic Hepatitis D)